Gangnam
Dr. Yoongon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices
Injection treatment at Reberry Clinic is a consultation-led menu of non-surgical micro-injections that smooth wrinkles, restore lost volume, regenerate collagen and refine facial and body contour, with no incisions and little to no downtime. Rather than a single product, it groups several injectable families, botulinum toxin for muscle relaxation and slimming, polynucleotide for skin repair and hydration, PDLLA for gradual collagen stimulation, and hyaluronic acid fillers for immediate volume, so the right combination can be matched to your skin, anatomy and goals. International patients are treated across three Seoul-area locations (Gangnam, Myeongdong, Incheon Airport) with English-speaking support.
Injection treatment is a non-surgical menu of micro-injections that smooth wrinkles, restore lost volume, regenerate collagen and refine contour. It groups four main families: botulinum toxin for muscle relaxation and slimming, polynucleotide for skin repair, PDLLA for collagen stimulation, and hyaluronic acid fillers for volume, each chosen by consultation.
One-on-One guidance from a dedicated doctor, ensuring your skin is professionally monitored and treated from start to finish.
Fluent assistance in English, Japanese, and Chinese, making communication clear, respectful and comfortable for international patients.
Over 100,000 patients worldwide have received our personalized dermatological care, highlighting our expertise and reliable results.
Injection treatment delivers active substances directly into the skin or muscle through a fine needle or cannula, giving targeted, controlled placement and faster onset than topical or oral routes. In aesthetic medicine it is an umbrella term for several distinct injectable families rather than one product, and each works by a different biological mechanism to address wrinkles, volume loss, laxity or skin quality without surgery.
The four families used most often at Reberry Clinic are botulinum toxin (a neuromodulator that relaxes targeted muscles to soften expression lines and slim the masseter or calves), polynucleotide injections (salmon-DNA fragments that calm inflammation and stimulate repair), PDLLA collagen stimulators such as Juvelook (poly-D,L-lactic acid microspheres that trigger your own collagen over months), and hyaluronic acid dermal fillers (a gel that adds immediate, reversible volume). Because each behaves differently, a treatment plan often layers two or more for a smoother, more youthful and balanced result.
Treatment is performed by the clinic’s doctors after a personalized assessment of your skin condition, facial structure and aesthetic goals. There are no incisions and, for most injectables, little to no recovery time, making the menu well suited to international patients on a short visit to Seoul.
Botulinum Toxin Injections — muscle relaxation, slimming and contour refinement. A neuromodulator that temporarily relaxes targeted muscles to soften dynamic wrinkles and reduce muscle bulk, commonly used for forehead and frown lines, masseter (jaw) slimming, calf reduction, and excessive underarm sweating.
How it works: the toxin blocks the nerve signal that tells a muscle to contract, so overactive muscles relax; in the underarm it blocks the sweat-gland signal for lasting dryness. Ideal for: expression lines, a square or heavy jawline, bulky calves, or facial tension. Results timeline: slimming or sweat-reduction effects appear within 3 to 14 days and generally last 3 to 6 months. Explore dedicated botox injection options at the clinic.
PDLLA Collagen-Stimulating Injections (Juvelook) — skin regeneration and collagen stimulation. A non-surgical injectable that uses poly-D,L-lactic acid microspheres to stimulate the skin’s own collagen production, improving elasticity, texture, fine lines and overall volume gradually and naturally.
How it works: Juvelook is injected into the skin, where the PDLLA particles act as a scaffold that prompts fibroblasts to build new collagen over the following weeks. Ideal for: early signs of aging, fine wrinkles, enlarged pores and mild volume loss. Results timeline: initial improvement appears within a few weeks, with collagen-driven results building progressively over 2 to 6 months and typically refreshed across a short series of sessions.
Polynucleotide (PN) Injections (Rejuran) — skin repair and rejuvenation. A non-surgical injectable that uses purified polynucleotides (salmon-derived DNA fragments) to calm inflammation, boost hydration and support tissue repair, improving skin texture, fine lines and elasticity from within.
How it works: Rejuran Healer is injected into the dermis, where polynucleotides stimulate fibroblast activity, encourage collagen synthesis and accelerate cellular repair for a healthier, more resilient complexion. Ideal for: dull or damaged skin, fine lines, large pores and early aging. Results timeline: skin-quality improvements typically build over a course of 3 to 4 sessions spaced 2 to 4 weeks apart, with effects maturing over several weeks.
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The before-and-after results of injection treatment reflect individual plans built around each person’s skin condition, anatomy and goals — not a single guaranteed outcome. Because the menu combines neuromodulators, biostimulators, polynucleotides and fillers, the change you see depends on which injectables are used and how they are layered. Results vary from person to person and develop on different timelines, so a consultation is the most reliable way to understand what injection treatment can realistically achieve for you.
Established in August 2023, Reberry Clinic earned certification as a medical institution for foreign-patient care by November 2023, and has since welcomed growing numbers of international patients, with a notable rise from June to July 2024. The clinic’s doctors deliver injection treatments with English-speaking support, and three Seoul-area locations (Gangnam, Myeongdong and Incheon Airport) make care convenient for visitors arriving or departing.
For your convenience, our treatments are available at three Seoul branches. Our Incheon Airport Branch, ideal for travelers, offers quick and easy care just minutes from the terminals. Our Myeongdong Branch is located in the city center near popular tourist attractions, and our Gangnam Branch is situated in Seoul’s upscale district, perfect for those looking to combine premium care with shopping, dining, or business.
At Reberry Dermatology Clinic , we believe in transparent and equitable pricing for all our patients, irrespective of their nationality. We guarantee that there will be no hidden fees or discriminatory charges.
We use advanced, FDA-approved machines to deliver high-performance results, all without the premium cost.
At Reberry Clinic, the head doctor conducts personalized consultations, building trust through expert guidance and tailored advice.
We deliver top-tier, personalized dermatological care at competitive rates, ensuring outstanding value and service.
Your injection-treatment journey begins with a personalized one-on-one consultation. The clinic’s doctor reviews your concerns, skin type, facial structure and aesthetic goals, then explains which injectable families, botulinum toxin, polynucleotide, PDLLA or hyaluronic acid filler, are most appropriate and how they may be combined. This assessment sets a tailored plan, including how many sessions your chosen injectables are likely to need.
On the day of treatment, a topical anesthetic is applied for comfort where needed, and the clinic’s doctor uses fine needles or a blunt cannula to place each product precisely into the target layer, muscle for toxin, dermis for polynucleotide or PDLLA, and deeper planes for volumizing filler. Most sessions take roughly 15 to 40 minutes depending on the number of areas, and the technique prioritizes safety, accurate placement and a natural-looking result with minimal downtime.
After injection treatment, any mild swelling, redness or small bruises usually settle within hours to a few days. Toxin effects emerge over 3 to 14 days, filler volume is visible immediately, while polynucleotide and PDLLA results build progressively over several weeks. With sensible aftercare and recommended maintenance, your refreshed, smoother appearance can be sustained over the long term.
Every face is unique, and your skin deserves a treatment plan tailored specifically to you. Start with a complimentary consultation where our expert team will design a personalized injection treatment plan based on your facial structure, skin condition, and aesthetic goals.
Don’t wait to reveal a fresher, more youthful you. Book your consultation today and take the first step toward a natural lift with injection treatment
These three injectable families each treat a different concern — muscle movement, skin quality and volume — so they are often combined rather than chosen against one another.
| Botulinum Toxin | Polynucleotide (Rejuran) | Hyaluronic Acid Filler | |
|---|---|---|---|
| Mechanism | Neuromodulator; relaxes targeted muscles | Salmon-DNA fragments; calm inflammation and stimulate repair | Cross-linked gel; adds immediate volume |
| Best for | Dynamic wrinkles, jaw or calf slimming, sweating | Dull, damaged skin; texture, fine lines, hydration | Volume loss, deep folds, contouring |
| Pain / comfort | Quick pinpricks; very tolerable | Multiple micro-injections; mild stinging | Pinch or pressure; numbing or built-in anesthetic helps |
| Downtime | None; rare small bruise | Minimal; transient bumps and redness | Minimal; possible swelling or bruising |
| Results timeline | Builds over 3-14 days | Gradual over several weeks across a course | Immediate, settling over 1-2 weeks |
| Longevity | About 3-6 months | Several months; maintained with top-ups | About 6-18 months by product and area |
| Sessions | Single visit, repeated periodically | Short course of 3-4, then maintenance | Single visit, repeated as needed |
The injectable families grouped under injection treatment are each supported by peer-reviewed clinical research. For botulinum toxin contouring, a prospective, randomized, double-blinded controlled trial of calf (gastrocnemius) injection recorded a significant decrease in calf circumference at 8 weeks (36.35 cm before versus 35.87 cm after; P = 0.03), and a phase 2 randomized study of masseter injection showed measurable reduction in masseter prominence versus placebo. For polynucleotide repair, a systematic review of esthetic use found consistent improvements in skin elasticity, hydration and texture across split-face trials, several conducted in Korean populations. For PDLLA collagen stimulation, a prospective study of Juvelook reported Global Aesthetic Improvement Scale scores rising from 1.48 at baseline to 2.16 at 24 weeks across five sessions, and a randomized split-face study evaluated PDLLA for photoaged skin. Hyaluronic acid filler durability has been quantified in a systematic review of 24 studies and 1,410 patients. These findings support gradual, mechanism-specific improvement, with results commonly seen in the Asian patients treated at our clinic.
Injection treatment is an umbrella term for several non-surgical injectable families delivered through a fine needle or cannula, including botulinum toxin, polynucleotide, PDLLA collagen stimulators and hyaluronic acid fillers. Each works by a different mechanism to smooth wrinkles, restore volume or improve skin quality. See our injection treatment page for the full menu.
The right injectable depends on your main concern. Botulinum toxin suits dynamic wrinkles and muscle slimming, polynucleotide suits dull or damaged skin, PDLLA suits gradual collagen loss, and hyaluronic acid filler suits immediate volume. A personalized consultation with the clinic’s doctor confirms which one, or which combination, best fits your skin and goals.
Injection treatment suits most healthy adults who want smoother, firmer or more volumized skin without surgery, especially those addressing wrinkles, mild laxity, dullness or volume loss. It is not suitable during pregnancy or breastfeeding, or over an active skin infection. Book a consultation so the clinic’s doctor can confirm suitability for you.
Most patients describe injections as a brief pinch or stinging sensation that is generally well tolerated. To improve comfort, a topical numbing cream is applied beforehand and very fine needles or a blunt cannula are used. Sensation stops as soon as each injection is placed, and no recovery period is needed for most products on the menu.
Downtime is usually minimal. Most people return to daily activities the same day, though mild swelling, redness or small bruises can appear at injection sites and typically resolve within a few hours to a few days. This low-downtime profile makes injection treatment convenient for international patients being treated during a short stay in Seoul.
Timelines differ by injectable: hyaluronic acid filler shows volume immediately, botulinum toxin develops over 3 to 14 days, while polynucleotide and PDLLA build gradually over several weeks. Longevity ranges from about 3 to 6 months for toxin to roughly a year or more for collagen-stimulating products, depending on the product, your metabolism and aftercare.
Session counts vary by product. Botulinum toxin and hyaluronic acid filler often work in a single visit, repeated periodically, while regenerative injectables such as polynucleotide or Juvelook usually need a short initial course of 2 to 4 sessions for full effect. The clinic’s doctor sets the exact schedule during your consultation.
Hyaluronic acid fillers add volume by placing a gel beneath the skin, immediately smoothing folds or restoring fullness. Botulinum toxin instead relaxes overactive muscles to soften dynamic wrinkles or slim areas like the jaw or calves. They address different problems, volume versus muscle movement, and are frequently combined within one personalized plan.
Rejuran is a polynucleotide injection of purified salmon-DNA fragments that calm inflammation, boost hydration and stimulate the skin’s own repair, improving texture, fine lines and elasticity. It targets overall skin quality rather than adding volume, and is usually given as a short course of sessions for results that mature over several weeks.
Yes. Layering injectables is common: toxin for movement, filler for volume, and polynucleotide or PDLLA for skin quality often complement one another within a single plan. The clinic’s doctor sequences and times each product so effects do not overlap unsafely and each works to its full potential. Your combination is decided during consultation.
Yes. Many patients pair injectables with energy-based lifting such as Thermage FLX or ultrasound lifting, since injections restore volume or skin quality while energy devices tighten existing collagen. Timing matters, so the clinic’s doctor plans the order across visits to keep treatment safe and effective for your goals.
Injection treatment is generally safe when performed by qualified medical staff using approved products. Side effects are usually mild and temporary, such as bruising, swelling or redness at the injection site. Serious complications are rare. A consultation reviews your medical history and any contraindications before treatment to keep your plan as safe as possible.
The most common side effects are minor and short-lived: redness, swelling, tenderness or small bruises at injection points, usually fading within hours to a few days. Less commonly, lumpiness or asymmetry can occur and is managed by the clinic’s doctor. Choosing an experienced provider and following aftercare reduces the likelihood of these effects.
Injection treatment is non-surgical: products are placed through a needle or cannula with no incisions, general anesthesia or extended recovery. Surgery permanently alters tissue, while injectables give adjustable, mostly temporary results that fade over months to a year or more. This makes injections a flexible, lower-commitment option, though results are not permanent and need maintenance.
Most injectables need little or no downtime, so they fit a short Seoul visit, though it helps to allow a day’s flexibility for any mild swelling or bruising. Reberry Clinic offers English-speaking support and three Seoul-area locations, including one at Incheon Airport, convenient for arrival or departure. Regenerative courses can be discussed for future visits.
Aftercare is simple: keep the area clean, avoid rubbing or massaging treated zones for a day, and skip intense heat such as saunas, vigorous exercise and alcohol for 24 to 48 hours. Daily sunscreen and good hydration support healing. The clinic’s doctor gives product-specific guidance and schedules any follow-up or maintenance sessions you need.
As an elective cosmetic procedure, injection treatment is generally not covered by insurance and is paid out of pocket. Cost depends on which injectables and how many areas your plan involves, so pricing is consultation-led rather than a fixed list. A consultation gives an accurate, individualized quote for your chosen treatment.
These three injectable families each treat a different concern — muscle movement, skin quality and volume — so they are often combined rather than chosen against one another.
| Botulinum Toxin | Polynucleotide (Rejuran) | Hyaluronic Acid Filler | |
|---|---|---|---|
| Mechanism | Neuromodulator; relaxes targeted muscles | Salmon-DNA fragments; calm inflammation and stimulate repair | Cross-linked gel; adds immediate volume |
| Best for | Dynamic wrinkles, jaw or calf slimming, sweating | Dull, damaged skin; texture, fine lines, hydration | Volume loss, deep folds, contouring |
| Pain / comfort | Quick pinpricks; very tolerable | Multiple micro-injections; mild stinging | Pinch or pressure; numbing or built-in anesthetic helps |
| Downtime | None; rare small bruise | Minimal; transient bumps and redness | Minimal; possible swelling or bruising |
| Results timeline | Builds over 3-14 days | Gradual over several weeks across a course | Immediate, settling over 1-2 weeks |
| Longevity | About 3-6 months | Several months; maintained with top-ups | About 6-18 months by product and area |
| Sessions | Single visit, repeated periodically | Short course of 3-4, then maintenance | Single visit, repeated as needed |
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