human dna diagram illustrating effect of adipose derived stem cell
Our Expertise

Adipose-Derived
Stem Cell Treatment

Renew your skin’s natural vitality and support elasticity with Reberry Clinic’s adipose-derived stem cell treatment, a consultation-led regenerative option that works with your own biology. Using stem cell-rich material drawn from your own fat tissue, this minimally invasive therapy aims to support deep cellular repair and gradual skin rejuvenation, helping soften fine lines and improve skin quality over time. It is offered as a non-surgical alternative for adults seeking natural-looking, progressive results rather than an instant change, with English-speaking support across our three Seoul-area locations.

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Adipose-derived stem cell treatment at Reberry Clinic uses stem cell-rich material from your own fat tissue, plus its growth factors, to support the skin’s natural repair, collagen and elasticity. This consultation-led, minimally invasive option suits adults wanting gradual, non-surgical skin rejuvenation. Results build over several weeks with little downtime, and outcomes vary by individual.

Doctor-Designated Care

One-on-One guidance from a dedicated doctor, ensuring your skin is professionally monitored and treated from start to finish.

Multilingual Comfort

Fluent assistance in English, Japanese, and Chinese, making communication clear, respectful and comfortable for international patients.

100,000+ Patients Treated

Over 100,000 patients worldwide have received our personalized dermatological care, highlighting our expertise and reliable results.

What is Adipose-Derived Stem Cell Treatment?

Adipose-Derived Stem Cell Treatment is a regenerative form of stem cell therapy that uses stem cell-rich material harvested from your own fat (adipose) tissue to support skin repair and gradual anti-aging benefits. Adipose tissue is a comparatively abundant source of regenerative cells, and the material is valued largely for the growth factors and signalling proteins it carries, which help support fibroblast activity, collagen renewal and skin elasticity.

After a small amount of fat is gently collected, the stem cell-rich fraction is prepared under sterile conditions and reintroduced into the body through precise microinjections, where it works locally to support the skin’s own repair processes. The aim is natural skin renewal and improved skin quality without surgery or synthetic fillers.

It is important to be realistic about scope: this is an aesthetic, skin-focused regenerative treatment, not a cure for any disease, and it is not FDA-approved for skin rejuvenation. Results vary between individuals and develop gradually. The treatment is performed at Reberry Clinic by the clinic’s doctors, and a personalized consultation is the only way to confirm whether it is appropriate for you. You can also compare our blood-derived stem cell pathway.

hands of aesthetic medicine specialists assessing face of a girl for stem cell treatment

Advanced Regenerative Science

Adipose-derived stem cell treatment uses a carefully controlled process that extracts stem cell-rich fluid from the patient’s own fat tissue, prepared under sterile medical protocols to preserve its regenerative components. The value of this material lies in the growth factors, cytokines and signalling proteins it contains, which communicate with surrounding tissue.

When reintroduced through precise microinjections to targeted skin areas, these natural factors are intended to support deep tissue repair, encourage collagen production and help maintain skin elasticity, without invasive surgery. Because the approach relies on your body’s own repair timeline, the effect is gradual and cumulative rather than immediate, and outcomes differ from person to person.

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Our Clinics

Visit Reberry Clinic across Seoul, Korea

One Reberry Clinic, multiple Seoul-area locations. Pricing & current promotions are listed on each branch's own site — tap a clinic to view pricing & book.

ONE REBERRY CLINIC · MFDS-REGISTERED DEVICES · MULTILINGUAL CARE AT EVERY LOCATION

Benefits of Adipose-Derived Stem Cell Treatment

Key Benefits of Adipose-Derived Stem Cell Therapy

benefits of adipose derived stem cell treatment
How it works

How Adipose-Derived Stem Cell Treatment Works?

illustration of how adipose derived stem cell treatment works
Stem Cell Extraction and Activation

A small amount of fat tissue, typically a few millilitres, is gently collected from your body through a simple, minimally invasive procedure. Using established laboratory techniques, the stem cell-rich fraction is then isolated from the fat and prepared under sterile conditions to preserve its regenerative growth factors. This careful preparation readies the autologous material to support your skin’s natural repair and renewal.

The prepared stem cell-rich material is reintroduced into your skin through precise, minimally invasive microinjections, targeting the areas you discussed with the clinic’s doctor. There, the growth factors it carries are intended to signal local repair, supporting collagen production and helping improve skin elasticity and texture over the following weeks, generally without surgery or general anesthesia. Most patients tolerate the session well with only mild, short-lived discomfort.

After treatment, your body gradually uses these regenerative signals to support repair and renewal in the treated skin. Over the following days and weeks, many patients notice smoother, firmer skin texture as collagen activity is supported. Because the process follows your own biological timeline, improvements are progressive, and a planned series usually reinforces them; individual results vary.

treatment options

Best Options for Body Inmode

bodyfx best option for body inmode treatment

BodyFX

For patients whose goals include lower-face contouring alongside skin rejuvenation, the clinic also offers complementary body-contouring options such as InMode BodyFX. BodyFX combines radiofrequency (RF) energy with high-voltage electrical pulses to reach the deeper fascial layer beneath the skin, helping to reduce localized fat such as a double chin for a more sculpted lower-face contour. It is a separate, device-based treatment from stem cell therapy, and any combination is planned during your consultation.

body forma best option for body inmode treatment

BodyForma

As a further complementary option, FORMA uses controlled radiofrequency (RF) energy that penetrates both the surface epidermis and the deeper dermis to support natural collagen and elastin activity. The aim is smoother, more supple skin with improved elasticity, texture and softened fine lines. Like BodyFX, FORMA is a distinct RF device treatment rather than a stem cell procedure; the clinic’s doctor advises whether pairing it with adipose-derived stem cell treatment suits your goals.

real results

Before, After, and Proven Results

Adipose-derived stem cell treatment is intended to support gradual improvements in skin tone, firmness and overall radiance while encouraging deeper cellular renewal. Each session is customized to your goals, and before-and-after expectations are discussed honestly during consultation. Results vary from person to person depending on skin condition, age and the area treated, and are not guaranteed; a consultation with the clinic’s doctor is the best way to understand what the treatment can realistically achieve for you.

A State-of-the-Art Clinic with Advanced Care

Reberry Clinic, established in August 2023, was certified to treat international patients by November of the same year. Since then, patients from around the world have visited for non-surgical anti-aging and regenerative skin care. Care is delivered by the clinic’s doctors across three Seoul-area locations (Gangnam, Myeongdong, Incheon Airport), with multilingual support in English, Korean, Thai, Japanese and Chinese, making personalized stem cell treatment convenient for international visitors.

3d facial skin analysis showing a realistic face and a wireframe model with a color scale map
a beautiful woman gently holding her cheek with one hand

Accessible Care for All Patients

We offer Adipose-Derived Stem Cell Therapy at all three of our Seoul branches. Our Myeongdong Branch is located in the city center near shopping, dining, and major tourist attractions. The Incheon Airport Branch is only minutes from Incheon International Airport, making it ideal for medical tourists looking for efficient, high-quality care. Our Gangnam Branch is situated in Seoul’s upscale district, perfect for those seeking premium treatments in a vibrant area known for beauty, business, and lifestyle.

Fair & Equal for All Patients

We believe in transparent, honest pricing. All patients whether local or international receive the same standard of care and pay the same fair rates. There are no hidden charges and no pricing differences based on nationality.

Advanced Stem Cell Technology

As a provider of advanced skincare treatments in Seoul, Korea, we use medically approved, high-grade systems to process and deliver stem cell therapy, including sterile lab techniques and FDA-compliant centrifugation. This ensures that every treatment is safe, effective, and held to the highest international standards.

Direct Doctor Consultations

Your care starts with a one-on-one consultation led by our head doctor. Every treatment plan is developed personally to match your wellness goals, ensuring clarity, confidence, and expert medical guidance at every step.

Premium Personalized Care

At Reberry, stem cell therapy is more than a procedure, it’s a personalized journey. From your first visit to long-term follow-up, we provide tailored regenerative care designed to restore your vitality, improve your skin, and support overall health, all at a competitive price.

Our process

Treatment Timeline & Expectations

01. Initial Consultation

Your journey starts with a consultation of around 60 minutes with the clinic’s doctor. During this session, your medical history is reviewed, your skin condition is assessed and your rejuvenation goals are discussed, so the doctor can confirm whether adipose-derived stem cell treatment is appropriate for you and design a personalized, consultation-led plan rather than a fixed package.

On the day of treatment, a small amount of fat, typically a few millilitres, is gently collected through a simple, minimally invasive procedure. The stem cell-rich fraction is then prepared under sterile conditions and reintroduced through precise microinjections to the agreed skin areas. The process is generally comfortable and does not require general anesthesia, and most patients are surprised by how straightforward the session feels.

Following treatment, you may notice mild redness, slight swelling or short-lived tenderness at the collection or injection sites, which usually settles within a day or two. Over the next several weeks, many patients find their skin gradually becomes firmer, smoother and more radiant as the regenerative signals support repair. Because results develop on your body’s timeline, patience is part of the process, and individual outcomes vary.

To support the best long-term results, the clinic’s doctor commonly recommends an initial series of around three treatments spaced roughly 2 to 4 weeks apart, followed by periodic maintenance sessions. Regular, planned care helps sustain the gradual anti-aging benefits and supports your skin’s natural renewal over time. The exact schedule is personalized to your skin and goals at consultation, with the same consultation-led pricing policy for everyone.

Post-Procedure Precautions

a woman with radiant facial skin

Safety & Information

Important Contraindications

Adipose-Derived Stem Cell vs Blood-Derived Stem Cell vs PRP

Adipose-derived stem cell treatment, blood-derived stem cell treatment and PRP are all autologous, regenerative options that differ in source and intensity — here is how they compare.

Adipose-Derived Stem CellBlood-Derived Stem CellPRP (platelet-rich plasma)
Source / mechanismStem cell-rich fraction from your own fat tissue plus growth factorsRegenerative fraction from a small blood drawConcentrated platelets from your own blood
Best forMore intensive, longer-horizon skin rejuvenationGentle, gradual skin-quality and hydration supportEntry-level skin texture and tone support
CollectionMinor fat collectionSimple blood drawSimple blood draw
Pain / comfortMild; brief soreness at the collection siteMild; similar to a routine blood drawMild; routine blood draw plus microinjection
DowntimeMinimal; redness or swelling for a day or twoMinimal; brief redness, possible light dizzinessMinimal; brief redness
Results timelineGradual over weeks, often longer-lastingGradual over a few weeksGradual over a few weeks
SessionsInitial series plus maintenanceSeries with maintenanceUsually a series of sessions

Scientific Evidence

Adipose-derived stem cells and their secreted factors are an active area of peer-reviewed dermatology research, though they remain investigational for aesthetic use rather than an approved cure. In a landmark histological study, intradermal autologous adipose-derived stem cell treatment produced de novo formation of oxytalan and elaunin elastic fibers in the sub-epidermal region and replaced disorganized elastotic deposits in the deep dermis with a more normal elastin fiber network. A comparative study of platelet-rich plasma versus adipose-derived stem cells reported structural improvement of photoaged dermis with both approaches. A 12-week randomized, split-face trial of adipose stem cell-derived exosome solution plus microneedling in 28 subjects reported measurable improvement in facial wrinkles, elasticity and skin quality. A 2025 investigator-blinded, split-face, non-inferiority trial found adipose stem cell exosomes increased collagen I and glycosaminoglycans comparably to PRP across 3- and 6-month follow-up. Korean and other split-face studies of stem cell conditioned media with microneedling likewise reported significant gains in skin elasticity. These findings support gradual, signalling-driven skin remodeling rather than instant or guaranteed transformation, and outcomes vary by individual.

  • Charles-de-Sá L, Gontijo-de-Amorim NF, Maeda Takiya C, et al. Antiaging Treatment of the Facial Skin by Fat Graft and Adipose-Derived Stem Cells. Plast Reconstr Surg. 2015;135(4):999-1009. doi:10.1097/PRS.0000000000001123
  • Charles-de-Sá L, Gontijo-de-Amorim N, Rigotti G, et al. Photoaged Skin Therapy with Adipose-Derived Stem Cells. Stem Cells Int. 2020;2020:2032359. doi:10.1155/2020/2032359
  • Park JH, Kim JE, Kim SH, et al. Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study. J Cosmet Dermatol. 2023;22(12):3418-3426. doi:10.1111/jocd.15872
  • Estupiñan HY, Wang T, Garcia MR, et al. Adipose Mesenchymal Stem Cell-Derived Exosomes Versus Platelet-Rich Plasma Treatment for Photoaged Facial Skin: An Investigator-Blinded, Split-Face, Non-Inferiority Trial. J Cosmet Dermatol. 2025;24(6):e70208. doi:10.1111/jocd.70208
  • Lee HJ, Lee EG, Kang S, et al. Efficacy of Microneedling Plus Human Stem Cell Conditioned Medium for Skin Rejuvenation: A Randomized, Controlled, Blinded Split-Face Study. Ann Dermatol. 2014;26(5):584-591. doi:10.5021/ad.2014.26.5.584
  • El-Domyati M, Moftah NH, Nasif GA, et al. Facial rejuvenation using stem cell conditioned media combined with skin needling: A split-face comparative study. J Cosmet Dermatol. 2020;19(9):2404-2410. doi:10.1111/jocd.13594
Faq

Got Questions?
We've Got Answers!

How long does an adipose-derived stem cell session take?

Each session typically lasts between 30 minutes and 1 hour, depending on the fat collection and injection process planned for you. This is usually preceded by a separate consultation where the clinic’s doctor assesses your skin. Because the procedure is minimally invasive, most of the time is spent on careful, sterile preparation of your own adipose-derived material.

Adipose-derived stem cell treatment for skin rejuvenation is generally not FDA-approved, so we describe it honestly as an investigational, supportive regenerative option rather than an approved cure. At Reberry Clinic, preparation follows strict sterile medical protocols using your own cells. A consultation lets the clinic’s doctor explain realistic expectations and exactly what the treatment can and cannot do.

Yes, adipose-derived stem cell treatment can often be combined with other skin or contouring treatments, such as Rejuran Healer or RF devices, to complement collagen support. Timing and sequence matter, so any combination is planned by the clinic’s doctor during consultation to create the safest, most effective personalized plan for your goals and skin condition.

The clinic’s doctor commonly recommends an initial series of around three treatments spaced about 2 to 4 weeks apart, followed by periodic maintenance sessions. Because regenerative effects build cumulatively, a planned series usually supports better and longer-lasting improvement than a single session. Your exact schedule is personalized at consultation based on your skin and goals.

A small amount of fat, typically a few millilitres, is gently collected through a minimally invasive procedure, then the stem cell-rich fraction is isolated and prepared under sterile, controlled laboratory conditions before being reintroduced by microinjection. This careful preparation preserves the regenerative growth factors. The clinic’s doctor performs and oversees the process with safety and sterility as priorities throughout.

Ideal candidates are generally healthy adults seeking natural, non-surgical anti-aging support who want to improve skin elasticity, texture and overall quality without major downtime. It suits people comfortable with gradual results that develop over weeks. Those with significant laxity may benefit more from energy-based Sofwave lifting, which a consultation will help clarify for you.

Most patients describe the treatment as mild and well tolerated. The small fat collection feels similar to a minor procedure, and the microinjections cause only brief discomfort, often eased with topical numbing. Because the approach is minimally invasive and uses no general anesthesia, there is no surgical pain, and the clinic’s doctor prioritizes your comfort at every step of the session.

Downtime is usually minimal. Most patients experience only mild redness, slight swelling or short-lived tenderness at the collection and injection sites, which typically settles within a day or two, and many resume normal activities quickly. This makes the treatment convenient for international patients being seen during a short stay in Seoul, with personalized aftercare guidance provided.

Improvements in skin firmness, texture and radiance generally develop gradually over several weeks as the regenerative signals support repair, rather than appearing immediately. Because the therapy follows your own biological timeline, results are progressive and build with a planned series. Outcomes vary between individuals, and your consultation provides a realistic timeline for your specific skin.

When performed by qualified professionals using your own cells, the treatment is generally well tolerated, with side effects usually limited to temporary redness, swelling, tenderness or minor bruising at the treated sites. Serious complications are uncommon with strict sterile protocols and proper aftercare. The clinic’s doctor reviews your medical history at consultation to confirm the treatment is safe and appropriate for you.

The clinic’s doctor will give personalized pre-treatment guidance at consultation, which may include staying well hydrated and avoiding certain medications or supplements that can affect bruising. It is important to share your full medical history and current medications honestly so the doctor can evaluate the treatment’s suitability and safety for you before proceeding with your adipose-derived stem cell plan.

Both are autologous regenerative options, but adipose-derived treatment uses stem cell-rich material from your fat tissue, while the blood-derived approach uses a simple blood draw. Fat is a comparatively rich source of regenerative cells, so adipose-derived treatment is often chosen for more intensive support. The clinic’s doctor recommends the best source for your goals at consultation.

Because the treatment uses your own autologous cells and works beneath the surface rather than targeting pigment, it is generally considered suitable across the full range of skin types and tones, including deeper Asian phototypes commonly treated at our clinic. A consultation still confirms it is appropriate for your specific skin condition, medical history and rejuvenation goals before any treatment begins.

No regenerative treatment is truly lasting, and we never present this as a permanent fix for aging. Improvements in firmness, texture and radiance are long-lasting but gradually fade as natural aging and environmental factors continue. Periodic maintenance sessions, good skincare and daily sun protection help sustain the benefits. Your consultation sets realistic expectations for how long results may last.

At Reberry Clinic this treatment is offered specifically for aesthetic, skin-focused rejuvenation, and we avoid making broad health or wellness claims it cannot support. While some patients describe feeling refreshed, the documented evidence centers on skin quality. The clinic’s doctor will keep expectations grounded in what the treatment is intended to do for your skin during consultation.

Because downtime is minimal, the treatment fits a short Seoul visit well. We suggest booking a consultation and treatment with a day’s flexibility for any mild swelling, and planning maintenance for future trips or local follow-up. Reberry Clinic offers English-speaking support and three Seoul-area locations, including stem cell therapy options convenient on arrival or departure.

Adipose-Derived Stem CellBlood-Derived Stem CellPRP (platelet-rich plasma)
Source / mechanismStem cell-rich fraction from your own fat tissue plus growth factorsRegenerative fraction from a small blood drawConcentrated platelets from your own blood
Best forMore intensive, longer-horizon skin rejuvenationGentle, gradual skin-quality and hydration supportEntry-level skin texture and tone support
CollectionMinor fat collectionSimple blood drawSimple blood draw
Pain / comfortMild; brief soreness at the collection siteMild; similar to a routine blood drawMild; routine blood draw plus microinjection
DowntimeMinimal; redness or swelling for a day or twoMinimal; brief redness, possible light dizzinessMinimal; brief redness
Results timelineGradual over weeks, often longer-lastingGradual over a few weeksGradual over a few weeks
SessionsInitial series plus maintenanceSeries with maintenanceUsually a series of sessions

Adipose-derived stem cell treatment, blood-derived stem cell treatment and PRP are all autologous, regenerative options that differ in source and intensity — here is how they compare.

Adipose-Derived Stem CellBlood-Derived Stem CellPRP (platelet-rich plasma)
Source / mechanismStem cell-rich fraction from your own fat tissue plus growth factorsRegenerative fraction from a small blood drawConcentrated platelets from your own blood
Best forMore intensive, longer-horizon skin rejuvenationGentle, gradual skin-quality and hydration supportEntry-level skin texture and tone support
CollectionMinor fat collectionSimple blood drawSimple blood draw
Pain / comfortMild; brief soreness at the collection siteMild; similar to a routine blood drawMild; routine blood draw plus microinjection
DowntimeMinimal; redness or swelling for a day or twoMinimal; brief redness, possible light dizzinessMinimal; brief redness
Results timelineGradual over weeks, often longer-lastingGradual over a few weeksGradual over a few weeks
SessionsInitial series plus maintenanceSeries with maintenanceUsually a series of sessions
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Our Doctors

Meet the Doctors Behind Reberry Clinic

Your treatment is planned and performed by experienced, MFDS-registered doctors across our Seoul-area clinics, with multilingual support for international patients.

Dr. Yoon-Gon Ryu — Aesthetic Medicine Specialist, Reberry Clinic Gangnam
Gangnam

Dr. Yoon-Gon Ryu

Aesthetic Medicine Specialist

Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)

Dr. Seung Jae Baek — Medical Director, Reberry Clinic Myeongdong
Myeongdong

Dr. Seung Jae Baek

Medical Director

Multilingual tourist care beside Myeongdong Cathedral

Dr. Seongjun Cho — Aesthetic Medicine Specialist, Reberry Clinic Incheon Airport
Incheon Airport

Dr. Seongjun Cho

Aesthetic Medicine Specialist

Fast, effective care 20 minutes from the terminals

Clinical Evidence

Peer-Reviewed Research

Published studies related to this treatment area. Individual results vary; consult a physician for personal advice.

  • J Pers Med · 2022 · PMID 35055432
    Adipose-Derived Stem Cells for Facial Rejuvenation
  • J Cosmet Laser Ther · 2018 · PMID 29394110
    Stem cell and skin rejuvenation
  • Plast Reconstr Surg · 2013 · PMID 23783059
    Nanofat grafting: basic research and clinical applications

Experience Trusted Adipose-derived Stem Cell Treatment in Korea — Same Price for Everyone

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