Gangnam
Dr. Yoongon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices
After a full course of 3 to 4 sessions spaced 2 to 4 weeks apart, Rejuran results typically last around 6 to 12 months before a maintenance session.
Rejuran results typically last about 6 to 12 months after a full course of 3 to 4 sessions spaced 2 to 4 weeks apart. The polynucleotide repairs skin gradually, so improvement builds over weeks and then fades slowly, which is why most people return for a maintenance session once or twice a year to sustain skin quality.
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Rejuran is a skin booster made from polynucleotides (PN), highly purified DNA fragments derived from salmon, injected into the skin to support repair and elasticity. Unlike a filler that adds volume, Rejuran works biologically: it helps the skin’s own fibroblasts and repair pathways function better, improving texture, fine lines, hydration and resilience over time. Because the effect comes from a temporary biological boost rather than a permanent implant, it naturally wears off as the polynucleotide is metabolized and the skin returns to its baseline rate of renewal.
That is why longevity is measured in months, not years. After a full induction course, most patients notice the benefit holding for roughly 6 to 12 months, with the exact duration depending on age, skin condition, sun exposure, smoking and overall skincare. Younger skin and well-protected skin tend to retain the effect longer, while sun damage and lifestyle stress shorten it. Rejuran is best thought of as ongoing skin maintenance rather than a one-time fix.
Reberry Clinic is a dermatology clinic serving international patients across three Seoul-area locations (Gangnam, Myeongdong, Incheon Airport) with English-speaking support. The clinic’s doctors assess your skin first and build a realistic schedule, so you know how many sessions to expect and when a maintenance visit will help sustain your Rejuran Healer results.
Rejuran’s active ingredient is polynucleotide (PN), a long-chain molecule of purified salmon-derived DNA. Once injected into the dermis, it acts as a biological scaffold and signaling support: it helps regulate inflammation, supports fibroblast activity and encourages a healthier extracellular environment. This is a gradual, cumulative process, which is why the visible benefit keeps building for several weeks after each session and why a course of 3 to 4 sessions is used to reach a meaningful, lasting result rather than a single shot.
The polynucleotide itself is naturally broken down and cleared by the body over weeks, so the improvement it triggers is sustained only as long as the skin’s renewed activity persists. As that settles, results plateau and then slowly decline, which is the basis for periodic maintenance. Because Rejuran improves skin quality rather than adding structure, it is often combined with energy or volume treatments; the clinic’s doctors will explain how it fits with options such as collagen-stimulating boosters when relevant to your goals.
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A full course is usually 3 to 4 sessions spaced 2 to 4 weeks apart to establish the result.
Improvement in texture and elasticity builds over the 4 to 8 weeks following each session, not overnight.
Most patients reach peak skin quality roughly 1 to 2 months after completing the course.
Results typically hold for 6 to 12 months, then fade gradually as the polynucleotide is cleared.
A single maintenance session every 6 to 12 months sustains the benefit for most patients.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
An English-language consultation assesses your skin and sets a course, typically 3 to 4 sessions, with a maintenance plan.
After numbing cream, the doctor injects Rejuran across the area; a session usually takes around 20 to 30 minutes.
Each session is spaced 2 to 4 weeks apart, so a full course spans roughly 6 to 12 weeks.
Improvement builds over 4 to 8 weeks per session, peaking 1 to 2 months after the final visit.
Results hold around 6 to 12 months; SPF, good skincare and a maintenance session help sustain them.
Rejuran results typically last about 6 to 12 months after a full course of 3 to 4 sessions. Because the polynucleotide is gradually metabolized, the benefit fades slowly rather than ending abruptly. Most patients return for a maintenance session within a year, which is mapped during your Rejuran Healer consultation.
A full course is usually 3 to 4 sessions spaced 2 to 4 weeks apart, which is what establishes durable improvement; a single session gives only a brief boost. After the course, one maintenance session every 6 to 12 months sustains the effect. Your exact schedule is set after the doctor assesses your skin.
No, Rejuran is not a one-time fix; it improves skin quality for months rather than indefinitely, because the polynucleotide is naturally cleared by the body. Think of it as ongoing skin maintenance. The benefit holds roughly 6 to 12 months before a maintenance session is recommended to keep results going.
Improvement is gradual, building over 4 to 8 weeks after each session as skin repair increases, with the fullest effect about 1 to 2 months after completing the course. Patience is part of the treatment. The expected timeline for your skin is explained during your assessment before the first session.
Most patients feel small pinches during the injections, which is generally manageable, and numbing cream is applied first to improve comfort. Mild stinging can occur as the product settles. Comfort options and the technique are reviewed during the Rejuran Healer consultation before treatment.
Downtime is usually minimal: small bumps, redness or mild bruising at injection points typically settle within a few hours to a couple of days. Most people return to normal activities the same day. This makes it practical for travelers, and aftercare to speed recovery is provided in writing.
Sun protection is the biggest factor, since UV damage shortens the benefit; daily SPF, good skincare, not smoking and adequate hydration all help. Completing the full course and timely maintenance also matter, and a gentle glass-skin routine can support overall skin quality between sessions for more consistent results.
Rejuran improves skin quality and lasts around 6 to 12 months, whereas fillers add volume and last differently by type. They do different jobs, so many patients combine them. To weigh options, discuss injectable fillers and Rejuran together so your plan matches both texture and volume goals.
Yes, Rejuran is often layered with collagen or energy treatments to build skin quality on more than one front, which many patients find more satisfying over time. The clinic’s doctors may suggest pairing it with a collagen-stimulating booster depending on your skin, sequencing sessions safely during your plan.
Yes, Rejuran is designed for repeat maintenance, and many patients have a session once or twice a year over the long term. Because it supports the skin’s own repair rather than implanting material, ongoing use is well tolerated for most people. Your suitability is reviewed at each visit before treatment.
No, longevity varies with age, skin condition, sun exposure and lifestyle, so the 6-to-12-month range is an average, not a guarantee. Younger, well-protected skin tends to hold results longer. This is why the clinic individualizes your maintenance timing rather than promising a fixed duration for every patient.
Yes, because Rejuran works in the dermis rather than targeting pigment, it suits a wide range of skin tones, including Asian and darker skin, when performed correctly. It is widely used across Asia. Your suitability and any precautions are confirmed during the assessment before your first session.
Yes, Reberry Clinic serves international patients with English-speaking support across three Seoul-area locations, including one near Incheon Airport. You can start a course on your trip and continue maintenance later. Message us on WhatsApp to plan a schedule that fits your stay and travel dates.
A single session takes only about 20 to 30 minutes, so even a short trip works for one visit; a full course needs several visits spaced weeks apart, which many travelers split across trips or start in Seoul. Our team helps you schedule sessions around your itinerary and plan maintenance from abroad.
Yes, most patients fly the same or next day, since downtime is minimal and any small bumps or redness settle quickly. The skin improvement then continues gradually after you return home. You receive a written aftercare plan so you can follow up on your Rejuran Healer results from abroad.
| Rejuran Healer | Juvelook | Hyaluronic Acid Booster | |
|---|---|---|---|
| Mechanism | Polynucleotide (PN) skin repair | PDLLA collagen stimulator | Hydrating hyaluronic acid |
| Main benefit | Skin texture, elasticity, fine lines | Gradual collagen and firmness | Hydration and glow |
| Typical longevity | About 6 to 12 months | Often around a year or more | Around 3 to 6 months |
| Sessions for a course | 3 to 4 | Usually 1 to 3 | 2 to 4 |
| Build time | Gradual over weeks | Gradual over months | Faster, shorter-lived |
| Best for | Repair and overall skin quality | Collagen volume and firmness | Quick hydration boost |
| Cost context | Consultation-led; depends on sessions | Consultation-led; depends on vials | Consultation-led; depends on sessions |
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