Gangnam
Dr. Yoon-Gon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)
Rejuran is a Korean polynucleotide (PN/PDRN) skin booster made from purified salmon DNA, injected across about 3 to 4 sessions spaced 2 to 4 weeks apart to improve skin quality from within.
Rejuran in Gangnam, Seoul is a polynucleotide (PN/PDRN) skin booster made from purified salmon DNA and micro-injected into the skin to improve elasticity, texture, and hydration from within. A typical course is about 3 to 4 sessions spaced 2 to 4 weeks apart, with minimal downtime, and the doctor tailors your plan at consultation.
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Rejuran is a Korean skin booster that uses polynucleotides (PN) and polydeoxyribonucleotides (PDRN) purified from salmon DNA to improve skin quality from the inside out. Rather than adding volume like a filler, it works as a regenerative treatment: fine micro-injections deliver the polynucleotides into the dermis, where they support the skin’s own repair processes. It is commonly chosen for fine lines, dullness, loss of elasticity, enlarged-looking pores, and overall skin fragility. At our Gangnam (Seoul) location, Dr. Yoongon Ryu tailors the injection plan to your skin.
Salmon DNA is used because it shares a high sequence homology with human DNA while avoiding the risks of mammalian-sourced material, and it is manufactured by PharmaResearch in Korea using a patented fragmentation technology. Because Rejuran conditions the skin rather than filling it, results appear gradually as the dermis is supported over a series of sessions, and it is often described as improving skin “quality” rather than reshaping contours.
Rejuran is consultation-led at Reberry Clinic: the doctor assesses your concerns, skin condition, and goals, then explains which Rejuran approach fits and how many sessions you are likely to need, transparently and in English. International patients are supported across our three Seoul-area locations, so a course can be planned around your travel dates.
Rejuran’s active ingredient is a polynucleotide chain (PN), a fragment of DNA purified from salmon and closely related to PDRN. Once micro-injected into the dermis, these fragments act largely through the adenosine A2A receptor, which studies link to reduced inflammation, increased fibroblast activity, and the release of growth factors such as VEGF. In practical terms, this supports angiogenesis (new micro-circulation), stimulates the skin’s own collagen and extracellular-matrix production, and helps rebalance an irritated or fragile skin barrier. Because the polynucleotides are hydrophilic, they also help the dermis hold water, which contributes to a more hydrated, plumped feel distinct from a hyaluronic-acid filler. Treatment is delivered as a series of tiny injections spaced about 2 to 4 weeks apart, usually 3 to 4 sessions, because the regenerative effect builds cumulatively as fibroblasts are stimulated over time rather than from a single dose. Salmon DNA is chosen for its high homology to human DNA and its low immunogenicity. The doctor sets injection depth, spacing, and technique per your skin thickness and concern so the polynucleotides are placed where they can best support repair.
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The doctor evaluates your skin quality, elasticity, and concerns, then plans a course usually of 3 to 4 sessions spaced 2 to 4 weeks apart.
Topical anaesthetic is applied for about 20 to 30 minutes so the many small micro-injections stay comfortable.
Polynucleotides are placed into the dermis via fine injections spaced across the treatment area, targeting the depth your skin needs.
Over the following weeks the polynucleotides act on the A2A receptor to reduce inflammation and stimulate fibroblasts, building collagen gradually.
Because the effect is cumulative, skin quality improves progressively across the 3 to 4 sessions rather than after a single visit.
Reberry Clinic · Prices verified: Oct 2026
| Clinic | Price (KRW) |
|---|---|
| GangnamPromotionalin the Gangnam medical district | from₩180,000 |
| MyeongdongStandardcity-center flagship | from₩240,000 |
| Incheon AirportStandardinside the airport, same-day visits | from₩220,000 |
VAT excluded · Final price depends on treatment scope and skin condition · Confirmed after consultation
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
At our Gangnam (Seoul) location, Dr. Yoongon Ryu assesses your skin quality and concerns, then explains which Rejuran approach fits and the 3 to 4 session plan, in English.
After about 20 to 30 minutes of numbing, the micro-injections take roughly 20 to 30 minutes depending on the area treated.
A course usually runs about 3 to 4 sessions spaced 2 to 4 weeks apart, because the regenerative effect builds cumulatively over time.
Early hydration and texture changes may appear within 2 weeks, while firmer, more elastic skin builds progressively over the following weeks and sessions.
Effects can hold for months, and periodic maintenance sessions help sustain skin quality. Sun protection and gentle skincare support results, which the doctor reviews with you.
Rejuran is a Korean polynucleotide (PN/PDRN) skin booster made from purified salmon DNA, micro-injected into the skin to improve elasticity, texture, and hydration from within. Unlike a filler, it is regenerative rather than volumising. You can read more on our Rejuran Healer page.
Rejuran is performed at our Gangnam (Seoul) location by Dr. Yoongon Ryu, about 2 minutes from Gangnam Station exit 10. Reberry Clinic supports international patients in English across three Seoul-area locations, so you can choose the branch and timing that best fit your visit to Seoul.
Rejuran delivers polynucleotides from salmon DNA into the dermis, where they act mainly through the adenosine A2A receptor to reduce inflammation, stimulate fibroblasts, and support collagen and barrier repair. Because the effect is regenerative and cumulative, skin quality builds gradually over a series of sessions rather than instantly.
No, Rejuran is a skin booster, not a dermal filler. It does not add contour or volume; instead it conditions the skin from within by supporting collagen and repair. For volume, other biostimulators differ in approach, which you can compare with our Juvelook page. Your doctor advises which suits your goals.
Most adults wanting better skin elasticity, texture, hydration, or resilience are suitable, especially for dull or fragile skin. Those seeking volume may need a different approach. A consultation, which you can start on our Rejuran Healer page, confirms whether Rejuran fits your goals.
Discomfort is well managed because topical numbing is applied for about 20 to 30 minutes before the micro-injections. Most people feel small pricks and mild pressure. Because Rejuran involves many tiny injections, numbing keeps it comfortable, and any sensitive areas are treated gently and adjusted by the doctor as needed.
Most people need about 3 to 4 sessions spaced 2 to 4 weeks apart, because the regenerative effect builds cumulatively as fibroblasts are stimulated over time. The exact number depends on your skin condition and goals. Your doctor maps a tailored plan at consultation and reviews progress as skin quality improves.
Downtime is minimal: small injection bumps, mild redness, or occasional bruising can appear and usually settle within a few days. Makeup is generally avoided for the first day. Because it is micro-injected rather than surgical, most people return to normal routines quickly, which suits travellers with limited time in Seoul.
Early hydration and texture changes may appear within about 2 weeks, while firmer, more elastic skin builds progressively over the following weeks and across the session series. Because Rejuran is regenerative, results are gradual and cumulative rather than immediate, with fuller improvement typically after the full course of 3 to 4 sessions.
Results can hold for several months, but Rejuran supports ongoing skin quality rather than being a one-time fix, so periodic maintenance sessions help sustain the improvement. Longevity varies with age, skin condition, and lifestyle. Diligent sun protection and a good skincare routine help extend how long results last between courses.
Yes, Rejuran is often paired with complementary treatments for firmer or glowing skin, depending on your goals. Any combination is planned by your doctor. For example, some patients also consider a glass facial skin approach for radiance. Your doctor advises what safely complements a regenerative plan.
Rejuran uses purified salmon DNA with high homology to human DNA and low immunogenicity, and is widely used in Korea with a favourable safety profile. Temporary redness, bumps, or bruising are the most common effects. A fish allergy, pregnancy, or bleeding tendencies require review first, so a consultation confirms it is safe for you.
Rejuran contains polynucleotides (PN), longer DNA fragments closely related to PDRN, both derived from salmon DNA. PN and PDRN share a regenerative mechanism via the A2A receptor, supporting repair and collagen. Rejuran is a specific Korean PN product. Your doctor explains which formulation and depth suit your skin at consultation.
Keep the area clean, avoid heavy makeup for the first day, skip saunas and intense exercise briefly, and use diligent sun protection while skin settles. Gentle hydration supports results. A supportive skin care routine helps you get the most from each session and protects your investment between visits.
Cost depends mainly on the treatment area, the specific Rejuran product used, and how many sessions your plan needs, so there is no single fixed figure. Reberry Clinic is consultation-led, so the doctor confirms your transparent, individualised cost in English after assessing your skin and goals.
For a single session, 1 to 2 days is enough because downtime is minimal, allowing a consultation and the treatment with a short review. Since a course runs 3 to 4 sessions, many international patients begin in Seoul and continue on return trips. Our English-speaking team helps coordinate session timing.
Yes, flying the next day is generally fine because Rejuran is a micro-injection treatment with minimal downtime. Cabin air is drying, so moisturise and protect skin from sun. Any small bumps or bruising typically settle within days, so travelling home shortly after a session does not usually affect your results.
International patients can complete a Rejuran course across one or more visits, and the clinic offers remote check-ins in English between trips so the plan stays on track. You can maintain results at home with a good skin care routine, and your treatment notes are kept on file for continuity.
These regenerative injectables all support skin from within but differ in material, mechanism, and whether they focus on skin quality or volume.
| Rejuran | Juvelook | Sculptra | |
|---|---|---|---|
| Material / mechanism | Polynucleotide (PN/PDRN) salmon DNA, regenerative | PDLLA collagen stimulator skin booster | PLLA collagen stimulator, volumising biostimulator |
| Best for | Skin quality, elasticity, fine lines, barrier repair | Skin firmness, glow, and fine-line smoothing | Gradual volume restoration and deeper support |
| Pain / comfort | Managed with topical numbing before micro-injections | Managed with topical numbing | Managed with topical numbing |
| Downtime | Minimal, small bumps or bruising settle over days | Minimal, mild swelling possible | Minimal to mild, occasional bruising |
| Results timeline | Builds over weeks across the session series | Builds gradually as collagen forms | Builds slowly over months as collagen forms |
| Sessions | Usually about 3 to 4, 2 to 4 weeks apart | A short series, plan-dependent | A series over months |
| Cost factors | Depends on area, product, and session count | Depends on area and session count | Depends on vials and treatment plan |
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