
Dr. Yoon-Gon Ryu
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Botulinum toxin injections block the nerve signals to sweat glands, cutting excessive underarm sweating for roughly 4 to 6 months per treatment.
Hyperhidrosis treatment in Myeongdong, Seoul uses botulinum toxin injected into the skin to block the nerve signal that triggers sweat glands, reducing excessive sweating for about 4 to 6 months. It is most commonly used for underarms, palms, and soles. At our Myeongdong (Seoul) location, Dr. Seung Jae Baek assesses and performs the treatment personally.
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Hyperhidrosis is excessive sweating beyond what the body needs to regulate temperature, most often affecting the underarms, palms, soles, and sometimes the scalp or face. It can be socially and professionally distressing. The most established non-surgical treatment uses botulinum toxin type A, injected in small amounts just under the skin, to temporarily block the chemical messenger (acetylcholine) that tells sweat glands to activate.
Once those signals are blocked, sweat production in the treated area drops sharply, usually within 2 to 7 days, and stays reduced for several months before the nerves gradually recover. A landmark trial found that 94 percent of patients responded at four weeks compared with 36 percent on placebo, making toxin injection one of the most reliable options for primary axillary (underarm) hyperhidrosis.
At Reberry Clinic, hyperhidrosis treatment is doctor-led. At our Myeongdong (Seoul) location, Dr. Seung Jae Baek, Medical Director, confirms the diagnosis, maps the sweat area, and performs the injections personally, explaining everything in English. International patients are supported across three Seoul-area locations, so treatment fits around travel plans.
Sweat glands are switched on by the neurotransmitter acetylcholine, released from small nerve endings in the skin. Botulinum toxin type A works by binding to those nerve terminals and preventing acetylcholine release, so the sweat glands in the treated zone no longer receive their activation signal. The effect is local and temporary: the toxin is placed in a grid of shallow micro-injections across the affected area, for example 15 to 20 points per underarm, so the whole sweating zone is covered evenly. Because it acts only where injected, sweating elsewhere on the body is unaffected and the body’s overall temperature regulation is preserved. Sweat reduction typically begins within 2 to 7 days and reaches full effect in about 2 weeks. As the nerve terminals slowly regenerate over 4 to 6 months, sweating gradually returns and the treatment can be repeated. A minimal-starch iodine (Minor’s) test is sometimes used first to map exactly where sweating is heaviest, so injections are concentrated where they matter most.
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The clinic’s doctors confirm primary focal hyperhidrosis and rule out secondary causes, as this shapes whether injection is the right option among 2 to 3 approaches.
A starch-iodine (Minor’s) test may be used to reveal exactly where sweating is heaviest, so injections are concentrated across those points.
For sensitive areas like palms, numbing cream or cooling is applied first; underarms are usually comfortable enough with minimal preparation.
Around 15 to 20 shallow injection points per underarm distribute the toxin evenly across the whole sweating area in a short session.
Sweating begins to fall within 2 to 7 days and reaches full effect at about 2 weeks as nerve signals to the glands are blocked.
The effect lasts roughly 4 to 6 months as nerves regenerate, then the treatment can be repeated to maintain dryness.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.





At our Myeongdong (Seoul) location, Dr. Seung Jae Baek confirms primary hyperhidrosis, maps the sweat area, and explains the plan in English.
After optional numbing, 15 to 20 shallow injections per underarm are placed; the whole session usually takes about 20 to 30 minutes.
It is a single-session treatment; sweating begins to drop within 2 to 7 days and reaches full effect by about 2 weeks.
Dryness typically lasts 4 to 6 months as nerve signals stay blocked, then gradually returns as nerves recover.
Treatment is repeated as the effect wears off; avoid heat and heavy exercise for 24 hours, and your doctor plans your next session timing.



Botulinum toxin blocks the nerve signal (acetylcholine) that activates sweat glands, so treated areas stop over-sweating for several months. It is injected in a grid of shallow micro-injections across the sweating zone. Learn more about how we perform toxin treatments on our botox injection page.
Most patients notice reduced sweating within 2 to 7 days, with full effect by about 2 weeks. Dryness typically lasts 4 to 6 months as the treated nerves stay blocked, then sweating gradually returns. The injection treatment can then be repeated to maintain the result.
It is highly effective for focal sweating. A landmark trial found 94 percent of patients responded at four weeks versus 36 percent on placebo, and many see sweat reduction of 80 percent or more. Underarm hyperhidrosis responds especially well to this botox injection approach, a well-established first-line procedure.
The most common area is the underarms, but palms, soles, the scalp, and the forehead can also be treated for excessive sweating. Each area is mapped and dosed individually. Because only injected zones are affected, sweating elsewhere on your body stays normal, preserving natural temperature control across the rest of your skin.
Underarm treatment is usually well tolerated with only brief stinging at each point. Palms and soles are more sensitive, so numbing cream, cooling, or nerve blocks are used to keep you comfortable. The session is short, with about 15 to 20 shallow injections per underarm placed quickly and evenly.
Downtime is minimal. You may see small red dots or mild tenderness at injection points that settle within hours. You can return to normal activities the same day. Avoid intense exercise, hot showers, and saunas for about 24 hours so the toxin settles precisely where it was placed.
No, the effect is strictly local to the injected area, so only the treated zone becomes dry while the rest of your body sweats normally. This preserves your natural temperature regulation. Some people notice slightly more sweat in untreated areas, which your doctor discusses and plans for during consultation.
Yes, botulinum toxin for hyperhidrosis is well studied and considered safe when performed by a trained doctor. A 52-week multicenter trial confirmed sustained efficacy and safety across repeated cycles. A consultation screens for contraindications like pregnancy or neuromuscular conditions to ensure the treatment is appropriate for you.
For underarms, roughly 15 to 20 shallow injection points per side spread the toxin across the whole sweating zone. Palms and soles need more points because the area is larger and more diffuse. Your exact plan is mapped at consultation, sometimes using a starch-iodine test to find the heaviest sweat areas.
Because the effect lasts about 4 to 6 months, most patients repeat treatment two to three times a year to stay dry. Some people find the interval lengthens slightly over time. Your doctor plans repeat timing around your response and schedule, so relief stays consistent throughout the year.
We use a clinic-appropriate, properly handled botulinum toxin type A of the generic category, dosed for the treated area. The clinic’s doctors explain suitability and dosing at consultation. Effective sweat control depends far more on accurate mapping and even placement than on any particular product brand.
Yes, some patients continue prescription antiperspirants between sessions or combine approaches for stubborn areas. Toxin injection is often the mainstay because it is targeted and reliable. If you have related concerns, our injection treatment options can be reviewed together during your consultation.
Good candidates have primary focal hyperhidrosis, especially of the underarms, that disrupts daily life and has not responded to antiperspirants. A consultation confirms the diagnosis and rules out secondary causes. Those who are pregnant, breastfeeding, or have neuromuscular conditions are usually not suitable, which your doctor checks before treatment.
Avoid vigorous exercise, hot showers, saunas, and rubbing the treated area for about 24 hours so the toxin stays where placed. You can resume most activities the same day, and support skin health with a gentle skin care routine. Your doctor gives simple written aftercare.
The procedure is a single quick session, so 1 to 2 days is enough for a consultation and treatment. Because results build over 1 to 2 weeks, you can fly home and see sweating drop afterward. Our English-speaking team helps time your visit and any repeat session around your travel.
Yes, flying the same day or the next day is generally fine, since hyperhidrosis injections are minimally invasive with little downtime. Avoid rubbing the treated area and skip heavy exercise while you travel. If you see minor redness at the points, it usually fades within hours during your journey home.
Hyperhidrosis treatment is available at our Myeongdong (Seoul) location at 5, Myeongdong 10-gil, Jung-gu, about 5 minutes from Myeongdong Station, with Dr. Seung Jae Baek as Medical Director. You can also read our botox injection page to learn more before booking a consultation.
| Botulinum Toxin Injection | Prescription Antiperspirants | Microwave Thermolysis | |
|---|---|---|---|
| Mechanism | Blocks nerve signal to sweat glands in the treated area | Aluminium salts plug sweat ducts on the surface | Microwave energy heats and reduces sweat glands |
| Best for | Focal underarm, palm, or sole sweating | Mild sweating or first-line at-home use | Underarm sweating seeking a longer-lasting reduction |
| Pain / comfort | Multiple fine injections, numbing for sensitive areas | Comfortable but can irritate skin | Requires local anaesthetic; more involved session |
| Downtime | Minimal, brief redness at injection points | None, but daily application needed | Swelling and tenderness for days to weeks |
| Results timeline | Dryness in 2 to 7 days, full effect by 2 weeks | Gradual, needs consistent nightly use | Reduction after treatment, may need repeat |
| Longevity | About 4 to 6 months, then repeated | Only while used regularly | Longer-lasting but more downtime |
| Cost context | Depends on area and number of units | Lowest, but ongoing | Higher per session, fewer sessions |
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