Rejuran Healer treatment
Our Expertise

Rejuran Healer near Hongdae Station, Seoul

Skin Booster

A polynucleotide skin booster that supports the skin’s own healing, delivered as a course of about 3 to 4 sessions spaced 2 to 4 weeks apart.

4.9

Rejuran Healer is a polynucleotide (PN/PDRN) skin booster made from purified salmon DNA fragments that improves skin elasticity, hydration, and texture over a course of about 3 to 4 sessions. For patients near Hongdae Station, care is provided across our Seoul locations in Gangnam and Myeongdong, with English-speaking doctors confirming your plan at consultation.

Doctor-Designated Care

One-on-One guidance from a dedicated doctor, ensuring your skin is professionally monitored and treated from start to finish.

Multilingual Comfort

Fluent assistance in English, Japanese, and Chinese, making communication clear, respectful and comfortable for international patients.

100,000+ Patients Treated

Over 100,000 patients worldwide have received our personalized dermatological care, highlighting our expertise and reliable results.

What is Rejuran Healer?

Rejuran Healer is a polynucleotide (PN/PDRN) skin booster derived from purified salmon DNA fragments, injected into the skin to support its own repair processes. Unlike a volumising filler that adds structure, Rejuran Healer works on skin quality — helping to improve elasticity, hydration, fine texture, and overall resilience gradually over a course of sessions.

It is popular with patients who want a natural, healthy-skin result rather than an obvious change in shape. Because polynucleotides act as a biostimulator, the improvement builds across a standard course of about 3 to 4 sessions spaced 2 to 4 weeks apart, with results maintained by occasional top-ups. Common treatment areas include the cheeks, forehead, and the delicate under-eye zone.

At Reberry Clinic, Rejuran care is consultation-led and multilingual. For international patients searching near Hongdae (Hongik Univ.) Station — 홍대입구역 — care is provided across our Seoul locations in Gangnam and Myeongdong, both easily reached from 홍대입구역, where the clinic’s doctors assess your skin and explain the plan in English before treatment begins.

Rejuran Healer treatment

How the polynucleotide technology works

Rejuran Healer’s active ingredient is polynucleotide (PN/PDRN), long chains of DNA fragments purified from salmon. Once placed into the skin through fine microinjections, these fragments act on the adenosine A2A receptor, a pathway shown to raise vascular endothelial growth factor and modulate inflammation. In practical terms, this supports the skin’s own healing cascade: better hydration retention, improved elasticity, and a smoother surface as the dermis is stimulated. Because the effect is regenerative rather than a filler-style plumping, it is delivered as a series so the skin can respond and rebuild between visits. A typical protocol involves 3 to 4 sessions at 2 to 4 week intervals, followed by maintenance every few months. The clinic’s doctors tailor the depth, number of syringes, and areas to your skin, and combine Rejuran with other approaches only where it makes sense. This regenerative mechanism is why Rejuran Healer is categorised as a skin booster, distinct from volumisers and energy-based lifting devices.

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Our Clinics

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Key Benefits

Key Benefits

Rejuran Healer treatment
How It Works

How Rejuran Healer Works

Rejuran Healer treatment
Consultation and mapping

Doctors assess your skin and map 1 to 3 areas to treat, then decide how many syringes and sessions your plan needs.

A topical anaesthetic is applied for about 20 to 30 minutes so the microinjections are comfortable.

Polynucleotide is placed into the skin through many fine microinjections, usually taking 10 to 20 minutes per area.

Over the following 2 to 4 weeks the skin responds, improving hydration and elasticity before the next session.

A standard course is 3 to 4 sessions, with top-ups every few months to maintain the result.

Comparison

Rejuran Healer vs Juvelook vs Revinas

Rejuran Healer treatment

Which Should You Choose?

Why It Suits You

Before & After

Real Before & After Results

See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.

Rejuran Healer before and after result 1 at Reberry Clinic
Rejuran Healer — result 1
Rejuran Healer before and after result 2 at Reberry Clinic
Rejuran Healer — result 2
Rejuran Healer before and after result 3 at Reberry Clinic
Rejuran Healer — result 3
Rejuran Healer before and after result 4 at Reberry Clinic
Rejuran Healer — result 4
Results vary by individual. Photos taken under standardized clinical lighting at Reberry Clinic during the 90–180 day post-treatment window.
The Process

Your Rejuran Healer Journey

Consultation

The clinic’s doctors assess your skin, map the areas, and explain the plan and expected timeline in English before you decide.

A session takes about 20 to 30 minutes including numbing, so it fits easily into a short visit near Hongdae Station.

A full course runs 3 to 4 sessions spaced 2 to 4 weeks apart, so results build across several weeks.

Many patients notice smoother, more hydrated skin after 2 to 3 sessions, with elasticity continuing to improve afterward.

Results are typically maintained with top-ups every few months alongside a gentle daily skincare and sunscreen routine.

Good Candidates

Cautions & Contraindications

Scientific Evidence

Studies of polynucleotide (PN/PDRN) skin boosters report measurable improvements in skin elasticity, hydration, and dermal thickness across a course of sessions. A Korean randomized, double-blind, split-face trial of 27 subjects treated the periocular area 3 times at 2-week intervals and found the polynucleotide side effective and safe for rejuvenation. Mechanistic reviews describe how PDRN activates the adenosine A2A receptor to raise VEGF and modulate inflammation, and a systematic review of 34 studies confirmed consistent wound-healing and tissue-regeneration effects, supporting the treatment’s regenerative, course-based approach.
  • Lee GY, et al. Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial. J Dermatolog Treat. 2022;33(1):254-260. doi:10.1080/09546634.2020.1748857
  • Rho NK, et al. A survey on the cosmetic use of injectable polynucleotide: the pattern of practice among Korean dermatologists. J Cosmet Dermatol. 2024;23(9):2793-2801. doi:10.1111/jocd.16125
  • Squadrito F, et al. Pharmacological activity and clinical use of PDRN. Front Pharmacol. 2017;8:224. doi:10.3389/fphar.2017.00224
  • Colangelo MT, et al. The effects of polydeoxyribonucleotide on wound healing and tissue regeneration: a systematic review of the literature. Regen Med. 2020;15(6):1801-1821. doi:10.2217/rme-2019-0118
  • Lampridou S, et al. The effectiveness of polynucleotides in esthetic medicine: a systematic review. J Cosmet Dermatol. 2025;24(1):e16721. doi:10.1111/jocd.16721
  • Chae JS, et al. Efficacy of ionization-adjusted PN filler in minimizing injection pain: a randomized, patient-blinded, split-face study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-05320-x
FAQ

Frequently Asked Questions

What is Rejuran Healer?

Rejuran Healer is a polynucleotide (PN/PDRN) skin booster made from purified salmon DNA fragments that supports the skin’s own healing, improving elasticity, hydration, and texture over a course. It is a skin-quality treatment rather than a volumiser. You can learn more on our Rejuran Healer page.

Patients searching near Hongdae (Hongik Univ.) Station are cared for at our Seoul locations in Gangnam and Myeongdong, both easily reached from 홍대입구역 with full English support. Your consultation and treatment are handled at these locations. See our Rejuran Healer page to begin.

Rejuran Healer improves skin elasticity, hydration, and fine texture by delivering polynucleotides that support the dermis’s own repair. Over a course of 3 to 4 sessions, skin often looks smoother, more supple, and healthier. It is regenerative rather than a plumping filler, so the change is natural and gradual.

Rejuran Healer improves skin quality using polynucleotides, whereas a volumising filler adds structure and shape. They solve different problems and are sometimes combined. If you want firmness and glow instead, you might consider Juvelook, which your doctor can compare for you at consultation.

A standard Rejuran Healer course is 3 to 4 sessions spaced about 2 to 4 weeks apart, allowing the skin to respond between visits. The exact number depends on your skin quality and goals. Your doctor reviews progress and adjusts the plan so you complete only the sessions your skin needs.

Discomfort is usually mild because a topical numbing cream is applied for about 20 to 30 minutes before the microinjections. Most patients describe a series of small pricks that are quickly over. Sensitive zones like the under-eye may feel a little more, and your doctor adjusts technique to keep you comfortable.

Downtime is minimal. Small bumps, mild redness, or slight bruising can appear at injection points and usually settle within a few days. Many patients return to normal activities the same day. Your doctor will advise avoiding heat, alcohol, and heavy exercise for a day or two to help the skin settle.

Skin quality typically improves gradually over several weeks, with many patients noticing smoother, more hydrated skin after 2 to 3 sessions. Because polynucleotides work by supporting healing, the effect builds across the course rather than appearing instantly after the first visit.

Results commonly last several months after a full course, though skin quality is maintained rather than fixed permanently. Most patients schedule top-ups every few months to sustain elasticity and hydration. A consistent skin care routine helps prolong the effect between sessions.

Yes, Rejuran Healer is often combined with hydrating skin boosters or energy-based treatments on separate visits for a fuller result. Some patients pair it with collagen-focused options like Revinas. Your doctor sequences treatments so they complement rather than overload the skin.

Common areas include the cheeks, forehead, and the delicate under-eye zone, where improved hydration and elasticity are especially visible. It can also be used on the neck. Your doctor maps which 1 to 3 areas suit your goals at consultation and tailors the number of syringes accordingly.

Most adults wanting better skin elasticity, hydration, and texture are suitable candidates. Because Rejuran is derived from salmon DNA fragments, a fish-DNA allergy is a contraindication. Pregnancy and active skin infection are also reasons to defer. A consultation confirms whether the treatment fits your skin and goals.

Rejuran Healer is widely performed in Korea and generally considered safe when a trained doctor matches technique and syringe count to your skin. Side effects are usually limited to temporary redness or small bumps. You can review the approach on our Rejuran Healer page before booking a consultation.

Aftercare is simple: keep the skin clean, use daily sunscreen, and avoid heat, alcohol, and heavy exercise for a day or two. A gentle skin care routine supports healing. Your doctor gives tailored aftercare advice so the skin settles well and results develop as expected.

For a first session, 2 to 3 days is comfortable, allowing a consultation, the procedure, and a short review. Because a full course runs over weeks, many international patients begin near Hongdae Station and continue on return visits. Our English-speaking team coordinates timing around your travel.

Yes, flying within a day is generally fine, as Rejuran Healer is minimally invasive with mostly short-lived redness or small bumps. Cabin air is drying, so moisturise and use sunscreen on treated skin. Your doctor will advise on aftercare so you can travel comfortably after your session.

International patients can complete a Rejuran course across one or more trips, and the clinic offers remote check-ins in English between visits so your plan stays on track. You can continue a supportive skincare routine at home, and your treatment notes are kept on file for continuity across visits.

Rejuran HealerJuvelookRevinas
MechanismPolynucleotide (PN/PDRN) skin healingPDLLA collagen-stimulating skin boosterFocused shockwave / acoustic-wave collagen support
Best forElasticity, hydration, and skin healingSkin firmness, glow, and fine linesNon-injection collagen stimulation and firmness
DeliveryFine microinjectionsInjection of PDLLA microspheresDevice-based acoustic waves, no injection
DowntimeMinimal, brief redness or small bumpsMinimal to mild, occasional swellingMinimal, no needle marks
Results timelineBuilds over the course of 3 to 4 sessionsGradual as collagen forms over weeksGradual over a series of sessions
Cost contextDepends on syringes and sessionsDepends on vials and areas treatedDepends on sessions and area size
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Our Doctors

Meet the Doctors Behind Reberry Clinic

Your treatment is planned and performed by experienced, MFDS-registered doctors across our Seoul-area clinics, with multilingual support for international patients.

Dr. Yoon-Gon Ryu — Aesthetic Medicine Specialist, Reberry Clinic Gangnam
Gangnam

Dr. Yoon-Gon Ryu

Aesthetic Medicine Specialist

Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)

Dr. Seung Jae Baek — Medical Director, Reberry Clinic Myeongdong
Myeongdong

Dr. Seung Jae Baek

Medical Director

Multilingual tourist care beside Myeongdong Cathedral

Dr. Sunbeen Kim — Chief Director, Reberry Clinic Incheon Airport
Incheon Airport

Dr. Sunbeen Kim

Chief Director

Fast, effective care 20 minutes from the terminals

Talk to us about Rejuran Healer near Hongdae Station

Message us on WhatsApp for a free consultation in English about whether Rejuran Healer suits your skin.

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