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How Long Palm Hyperhidrosis Treatment Lasts for International Patients

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Botox for palmar hyperhidrosis in Korea typically keeps the hands noticeably drier for about 4 to 6 months per session, with sweating dropping within the first week and a repeat scheduled as it slowly returns.

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Botox for palm hyperhidrosis in Korea typically keeps the hands drier for about 4 to 6 months per session, longer than facial Botox because sweat-gland nerves recover more slowly. Sweating drops within the first week. As the effect fades, palm sweating gradually returns, so most patients repeat about 2 to 3 times a year on a consultation-led interval.

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What Is Palm Hyperhidrosis Treatment?

Palm hyperhidrosis treatment uses botulinum toxin type A injected just under the skin of the palms to reduce excessive sweating. In one session, the clinic’s doctors place a grid of many small intradermal injections across each palm, temporarily switching off the nerve signal that drives the sweat glands. It is one of the most reliable non-surgical options for hands that stay damp regardless of temperature or stress.

Unlike facial Botox, which relaxes muscles, palm treatment targets the sweat glands, and that difference is why it tends to last longer, commonly about 4 to 6 months per session. The effect is temporary by design, so the honest answer to how long it lasts is a cycle: sweating stays controlled for several months, then gradually returns and is maintained with a repeat rather than a one-time fix.

Reberry Clinic is consultation-led and cares for international patients across three Seoul-area locations (Gangnam, Myeongdong, Incheon Airport) with English-speaking support. The clinic’s doctors assess sweat severity and plan a realistic maintenance rhythm rather than selling a fixed package.

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How Botox Controls Palm Sweating

Sweat glands are activated by acetylcholine, a nerve messenger. Botulinum toxin type A blocks the release of acetylcholine at the nerve endings feeding the eccrine sweat glands in the palm, so the glands stop being triggered and the skin stays dry. Because roughly 15 to 50 or more injection points cover each palm in a grid, the coverage is what determines how evenly the hands dry out.

The reason palm results outlast facial Botox is that these sweat-gland nerve endings regenerate slowly, so the anhidrotic (sweat-blocking) effect commonly persists about 4 to 6 months. Grip strength is generally preserved because the target is the sweat glands rather than the hand muscles. When sweating slowly returns, the clinic’s doctors repeat the grid, and can discuss combining care or other injectable treatments where relevant.

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Key Benefits

Key Benefits

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How It Works

How Palm Hyperhidrosis Treatment Works

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Map the palms

The clinic’s doctors assess sweat severity and mark a grid of about 15 to 50 or more injection points per palm.

Because palms are sensitive, a topical anesthetic or cooling is used for around 20 to 30 minutes before injecting.

Many small intradermal doses of botulinum toxin type A are placed across each palm in one session.

Palms become noticeably drier within about 2 to 7 days as the sweat-gland signal is blocked.

The dry effect typically holds about 4 to 6 months, so most patients repeat 2 to 3 times a year.

Comparison

Palm Botox vs Antiperspirants vs Microwave Device Treatment

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Before & After

Real Before & After Results

See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.

Botox Injection before and after result 1 at Reberry Clinic
Botox Injection — result 1
Botox Injection before and after result 2 at Reberry Clinic
Botox Injection — result 2
Botox Injection before and after result 3 at Reberry Clinic
Botox Injection — result 3
Botox Injection before and after result 4 at Reberry Clinic
Botox Injection — result 4
Botox Injection before and after result 5 at Reberry Clinic
Botox Injection — result 5
Results vary by individual. Photos taken under standardized clinical lighting at Reberry Clinic during the 90–180 day post-treatment window.
The Process

Your Palm Hyperhidrosis Treatment Journey in Seoul

Consultation

An English-language consultation assesses sweat severity and explains the likely 4 to 6 month maintenance interval for you.

With numbing, the session runs about 30 to 45 minutes in total, with no recovery stay needed afterward.

Because the visit is short with minimal downtime, even a one to two day Seoul stop accommodates a session.

Palms become drier within 2 to 7 days and the effect typically lasts about 4 to 6 months before a repeat.

Plan your next session at about 4 to 6 months; we help international patients schedule and follow up from abroad.

Good Candidates

Cautions & Contraindications

Scientific Evidence

Randomized and controlled studies consistently show a longer duration for palm treatment than for facial Botox. A double-blind, placebo-controlled trial reported clear reductions in gravimetric sweat production, and a randomized two-dose study found anhidrosis still evident in about two thirds of patients at six months, with significant reduction within the first month. Reviews of the evidence support a practical repeat interval near 4 to 6 months, which is why maintenance for palm sweating is scheduled around that window rather than the 3 to 4 months typical of muscle-relaxing facial Botox.
  • Lowe NJ, Yamauchi PS, Lask GP, Patnaik R, Iyer S. Efficacy and safety of botulinum toxin type A in the treatment of palmar hyperhidrosis: a double-blind, randomized, placebo-controlled study. Dermatol Surg. 2002;28(9):822-827. doi:10.1046/j.1524-4725.2002.02039.x
  • Saadia D, Voustianiouk A, Wang AK, Kaufmann H. Botulinum toxin type A in primary palmar hyperhidrosis: a randomized, single-blind, two-dose study. Neurology. 2001;57(11):2095-2099. doi:10.1212/wnl.57.11.2095
  • Rashaan R, Arkoumanis PT. The efficacy of botulinum toxin A in treating palmar hyperhidrosis: a literature review. Maedica (Bucur). 2023;18(4):712-717. doi:10.26574/maedica.2023.18.4.712
  • Wollina U, Karamfilov T. Botulinum toxin A for intracutaneous injection in palmar hyperhidrosis. J Eur Acad Dermatol Venereol. 2001;15(6):555-558. doi:10.1046/j.1468-3083.2001.00350.x
  • Naumann M, Lowe NJ. Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial. BMJ. 2001;323(7313):596-599. doi:10.1136/bmj.323.7313.596
  • Nestor MS, Ablon GR. Duration of action of abobotulinumtoxinA and onabotulinumtoxinA. J Clin Aesthet Dermatol. 2011;4(11):43-49. doi:10.25251/skin.1.supp.43
FAQ

Frequently Asked Questions

How long does palm hyperhidrosis treatment last?

Botox for palm sweating typically keeps the hands drier for about 4 to 6 months per session, longer than facial Botox because sweat-gland nerves recover slowly. As the effect fades, sweating gradually returns and you repeat to maintain. Your interval is set during the Botox consultation based on how your result holds.

Palm treatment targets sweat-gland nerve endings, which regenerate more slowly than the muscle nerves treated in facial Botox, so dryness commonly lasts about 4 to 6 months rather than 3 to 4. Duration still varies by person and dose. The clinic’s doctors track how long your hands stay dry to set the next repeat.

Most people notice noticeably drier palms within about 2 to 7 days as the sweat-gland signal is blocked. The change is fairly quick compared with skin treatments that build gradually. If any patchy areas remain, the clinic’s doctors can review coverage and adjust the injection grid at your next session.

Most patients repeat about every 4 to 6 months, which is roughly 2 to 3 sessions a year, because that is how long dryness usually holds. Heavier sweaters may need it slightly sooner. The clinic’s doctors set a Botox interval tailored to your sweat pattern rather than a fixed one.

Palms are sensitive, so a topical anesthetic or cooling is applied for about 20 to 30 minutes first, which makes the many small injections much more comfortable. You may feel brief pinches and mild soreness afterward. The whole visit runs around 30 to 45 minutes with numbing, and normal activity resumes the same day.

Grip strength is generally preserved because the injections target sweat glands just under the skin, not the deeper hand muscles. Some people feel brief, mild weakness or fatigue that settles within days. The clinic’s doctors use appropriate depth and dosing, reviewed alongside your Botox plan, to keep hand function normal.

No, palm hyperhidrosis treatment is not a one-time fix; the sweat-blocking effect wears off over about 4 to 6 months as nerve endings recover. It is a maintenance treatment repeated a few times a year. The clinic’s doctors plan a realistic rhythm so your hands stay dry rather than promising a single permanent result.

Downtime is minimal: most people return to normal activity the same day, with possible brief soreness, small bumps or minor bruising on the palms. Avoid heavy gripping or intense hand exercise for the rest of the day. This easy Botox recovery makes it convenient to fit around a short Seoul trip.

Yes, many patients treat palms and underarms in related sessions since both use the same sweat-blocking approach with botulinum toxin type A. Planning them together can be efficient. The clinic’s doctors assess each area’s severity and can coordinate an overall plan alongside your injectable options.

Often the first session gives a good sense of your personal duration, and later sessions tend to hold similarly at about 4 to 6 months. Response is individual, not fixed. The clinic’s doctors note how long your hands stayed dry after the first treatment to fine-tune dose and timing for the next.

Botulinum toxin type A has a long safety record for hyperhidrosis when dosed appropriately at sensible intervals. Repeating about every 4 to 6 months keeps within established guidance. The clinic’s doctors screen your history, confirm the sweating is primary rather than from another cause, and keep dosing measured for long-term safety.

Most side effects are mild and temporary, including brief soreness, small bumps, minor bruising and occasionally short-lived mild hand fatigue. Serious effects are uncommon with correct technique. The clinic’s doctors review your history and use appropriate depth and coverage to keep the palm treatment safe and comfortable.

Because the session is a single visit with minimal downtime, a one to two day stop in Seoul is enough; with numbing the visit runs about 30 to 45 minutes. You do not need to stay for recovery. Dryness then sets in over the first week, continuing after you fly home.

Yes, flying the same day is generally fine as there is no significant recovery period. Keep the palms clean, avoid heavy gripping and intense hand use for the day, and skip harsh scrubbing. Many international patients treat this as a quick add-on to a Seoul trip, with dryness developing over the following days after they travel onward.

You can repeat palm treatment on your visits to Korea; many international patients return to Reberry Clinic across its three Seoul-area locations, including one near Incheon Airport, every few months. We keep notes on your dose and grid so each Botox session stays consistent, and we support follow-up from abroad.

Palm BotoxPrescription antiperspirantsEnergy-based device treatment
MechanismBotulinum toxin type A blocks the sweat-gland nerve signalTopical salts plug and reduce sweat ductsFocused energy targets sweat glands in the skin
Best forModerate to severe palm sweating wanting reliable drynessMilder sweating or a first, at-home stepThose seeking a longer-term reduction, mainly studied for underarms
OnsetDrier within 2 to 7 daysGradual over days to weeks of useOver weeks after the session
DurationAbout 4 to 6 months per sessionOnly while applied regularlyLonger-lasting reduction from a course
ComfortBrief injections, palms numbed firstCan irritate the skinSome swelling or tenderness afterward
Cost contextConsultation-led; depends on palm size and unitsLower cost but ongoing useConsultation-led; device courses vary
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Dr. Yoongon Ryu — Aesthetic Medicine Specialist, Reberry Clinic Gangnam
Gangnam

Dr. Yoongon Ryu

Aesthetic Medicine Specialist

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Dr. Seung Jae Baek — Medical Director, Reberry Clinic Myeongdong
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Dr. Seung Jae Baek

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Dr. Seongjun Cho — Aesthetic Medicine Specialist, Reberry Clinic Incheon Airport
Incheon Airport

Dr. Seongjun Cho

Aesthetic Medicine Specialist

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