
Dr. Yoongon Ryu
Flagship clinic · KOL for leading lifting & regenerative devices

Anti-wrinkle botulinum toxin type A softens dynamic lines for about 3 to 4 months per session, with results appearing over roughly 3 to 7 days.
Anti-wrinkle treatment in Korea typically lasts about 3 to 4 months per session. Botulinum toxin type A relaxes the small facial muscles that fold dynamic lines such as frown lines, forehead lines, and crow’s feet, so they soften and smooth. Results appear over about 3 to 7 days, peak near two weeks, then gradually fade as muscle activity returns and the session is repeated.
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Anti-wrinkle treatment uses botulinum toxin type A to relax the small muscles that repeatedly fold the skin into dynamic lines, the wrinkles that deepen when you frown, raise your brows, or smile. Common targets are the glabella (frown lines between the brows), horizontal forehead lines, and lateral crow’s feet. By easing that muscle pull, the overlying skin creases less and existing dynamic lines look softer and smoother. It is non-surgical and the effect is temporary and repeatable.
Because people mainly want to know how long it lasts, the timeline matters. The result is not instant: softening begins over about 3 to 7 days, reaches its peak near two weeks, then holds for roughly 3 to 4 months before muscle activity gradually returns and lines reappear. This is why anti-wrinkle treatment is a maintenance routine rather than a one-time fix. Duration varies with the area treated, dose, individual metabolism, and how expressive or active the muscles are.
At Reberry Clinic, anti-wrinkle care is consultation-led. The clinic’s doctors assess which muscles drive your lines, plan dosing per area, and explain the expected duration and when to return. International patients are supported in English in Korea, so treatment and repeats can be timed around visits.

Botulinum toxin type A works at the neuromuscular junction: it blocks the release of acetylcholine, the signal a nerve uses to contract a muscle. With the signal muted, the treated muscle relaxes and stops folding the skin above it, so dynamic lines soften. The block is temporary. Over the following months the nerve terminals gradually recover and re-establish signalling, muscle movement returns, and the lines slowly reappear, which is why the effect commonly lasts about 3 to 4 months and is then repeated. Onset is gradual because the toxin needs a few days to act on the nerve terminals, so softening builds over about 3 to 7 days and peaks near two weeks. Different areas can last slightly differently: strong muscles like the frown complex and busy forehead may fade a little sooner, while some patients notice glabellar benefit for up to a few months longer. Randomized studies of glabellar and crow’s feet treatment, including trials in Korean patients, report most subjects benefiting for about 3 to 4 months, and repeated sessions maintain the result over time. Dose, area, and individual metabolism all shape how long a given result lasts.
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The clinic’s doctors examine which muscles drive your dynamic lines and grade severity, planning dosing across up to 3 common upper-face areas in about 1 consultation.
Dose is set per muscle group, since frown, forehead, and crow’s feet areas each need a tailored amount for an even, lasting result.
Botulinum toxin type A is placed into the target muscles with fine needles; the session usually takes about 10 to 15 minutes.
Softening begins over about 3 to 7 days and peaks near 2 weeks as the toxin acts on the nerve terminals.
Over roughly 3 to 4 months, muscle movement gradually returns and lines reappear, so the session is repeated to maintain smoothness.

See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.





The clinic’s doctors examine your dynamic lines, explain the expected duration, dosing, and cost transparently in English, and agree the areas to treat.
Treatment of the common upper-face areas usually takes about 10 to 15 minutes, with optional light numbing for comfort.
The visit is short, but the smoothing effect builds over the following days rather than being immediate.
Most people see softer lines within about 3 to 7 days, peaking near 2 weeks and holding for roughly 3 to 4 months.
Because movement gradually returns, sessions are repeated roughly every 3 to 4 months to keep dynamic lines soft.



Anti-wrinkle treatment commonly lasts about 3 to 4 months per session on dynamic lines, though this varies by area, dose, and individual metabolism. As movement gradually returns, the session is repeated. You can read more about the approach on our botox injection page.
Softening begins over about 3 to 7 days after treatment and peaks near two weeks, not immediately, as the toxin gradually acts on the nerve terminals. If a small area still moves after two weeks, your doctor can review and refine at a follow-up so the smoothing is even and lasts.
The effect fades because botulinum toxin only temporarily blocks the nerve signal to the muscle, and over months the nerve terminals recover and movement returns. This is normal and expected, which is why anti-wrinkle treatment is repeated roughly every 3 to 4 months rather than being a permanent, one-time fix.
The most common areas are frown lines between the brows, horizontal forehead lines, and lateral crow’s feet, since these are dynamic lines caused by muscle movement. Static lines at rest may suit other options. You can see related injectables on our injection treatment page.
Not always: strong muscles like the frown complex and busy forehead can fade a little sooner, while some people notice glabellar benefit lasting slightly longer. Duration typically sits around 3 to 4 months overall. Your doctor doses each area to your muscle strength so the result stays balanced and even.
Dose does influence duration, but your doctor sets it to your muscle strength and desired movement rather than simply maximising it. Too much can look overly still, while correct, area-specific dosing gives a natural softening that holds well across the usual 3 to 4 month window.
Discomfort is usually minor because fine needles are used and each area takes only moments, with the whole session about 10 to 15 minutes. Light numbing or cooling can be used for comfort. Most patients tolerate it easily, and comfort measures do not change how long results last.
Downtime is minimal and most people return to normal activity the same day, though small marks, redness, or brief tenderness are possible. Avoid rubbing the area, lying flat, and heavy exercise for the rest of the day. Your doctor gives specific aftercare so the result settles evenly.
Because each session lasts about 3 to 4 months, most people repeat treatment roughly 3 to 4 times a year to keep dynamic lines soft. Many settle into a comfortable rhythm. You can plan repeats around visits to Korea, and our botox injection page explains the approach.
With consistent repeat sessions, many people find lines look softer over the longer term because the muscles are used less between visits. Each individual session still lasts around 3 to 4 months. Your doctor tracks your response and adjusts timing so the smoothing stays natural and even over time.
Yes, anti-wrinkle toxin and fillers target different problems, so they are often combined: toxin relaxes dynamic lines while filler restores volume for static lines. Each lasts on its own timeline. You can compare related options on our injectable fillers page before your consultation.
Randomized studies and long-term reports show botulinum toxin type A is well tolerated for facial lines, with side effects usually mild and temporary. A proper consultation screens for contraindications like pregnancy or neuromuscular conditions. You can read how it is used on our botox injection page.
Most side effects are mild and short-lived, such as small bruises, mild headache, or temporary redness. Rarely, temporary brow or eyelid heaviness can occur if the toxin spreads, which resolves as the effect fades. Precise, area-specific dosing by your doctor keeps expression natural while softening lines.
Stay upright for a few hours, avoid rubbing or massaging the area, and skip heavy exercise, saunas, and alcohol for the rest of the day. Gentle skincare and sun protection support the skin. A supportive skin care routine keeps treated skin healthy while the effect settles.
A visit of 1 day is usually enough, as treating the common upper-face areas takes about 10 to 15 minutes with minimal downtime. Because softening builds over 3 to 7 days, many international patients fly home afterwards. Our English-speaking team helps you coordinate timing around your trip.
Yes, flying the same day or the next day is generally fine because the treatment is non-surgical with minimal downtime. Avoid rubbing the area during travel and stay upright for the first few hours. Results will continue to develop over the following week while you are back home.
International patients can be reviewed in English between visits, and repeat sessions are timed to your next trip to Korea before movement fully returns. Your treated areas and dosing are kept on file for continuity. You can plan the approach in advance on our botox injection page.
| Anti-Wrinkle Botulinum Toxin | Dermal Filler | Energy Skin Tightening | |
|---|---|---|---|
| Mechanism | Relaxes muscles that fold dynamic lines | Adds volume to soften static lines and folds | Heats deeper layers to stimulate collagen |
| How long it lasts | Commonly about 3 to 4 months, then repeated | Roughly several months to over a year by product | Gradual, building over months after a course |
| Best for | Dynamic lines from movement (frown, forehead, crow's feet) | Static lines and volume loss at rest | Overall laxity and texture rather than single lines |
| Onset | Builds over about 3 to 7 days, peaks near 2 weeks | Immediate volume, settling over 1 to 2 weeks | Gradual over weeks to months |
| Downtime | Minimal; small marks or brief tenderness possible | Minimal; some swelling or bruising possible | Minimal to short, device dependent |
| Cost context | Depends on areas and dose per session | Depends on product and volume used | Depends on device and number of sessions |
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