Gangnam
Dr. Yoongon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices
For sweaty palms, intradermal botulinum toxin type A typically reduces sweating within about 1 week, with the before-and-after difference lasting roughly 4 to 6 months.
In the before-and-after of palm hyperhidrosis treatment, botulinum toxin type A is injected across each palm to block the nerve signals that trigger sweating. Most patients notice dry, comfortable palms within about 1 week, with the effect typically lasting 4 to 6 months. Results are realistic and temporary, not a one-time fix, so treatment is repeated as sweating returns.
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Primary palmar hyperhidrosis is excessive sweating of the palms that is not caused by heat or exercise, and the before-and-after change after botulinum toxin treatment is one of the most noticeable in aesthetic medicine. Before treatment, palms may be visibly damp, drip during stress, smudge paper, or make handshakes and phone screens difficult. After a course of intradermal botulinum toxin type A, most patients describe palms that stay dry and comfortable through daily activities.
The treatment works because botulinum toxin type A temporarily blocks the chemical messenger that activates sweat glands. Many small injections, commonly around 1.5 to 2 units per point spread in a grid of dozens of points across each palm, reduce the overactive sweat response. The visible before-and-after difference usually appears within about a week and, in studies, can hold for roughly 4 to 6 months before sweating gradually returns and a repeat session is planned.
At Reberry Clinic in Seoul, Korea, palm hyperhidrosis treatment is consultation-led and popular with international patients seeking relief on a short trip. The clinic’s doctors assess how much your palms sweat, explain what a realistic before-and-after looks like, and support foreigners in English throughout the visit.
The before-and-after result comes from how botulinum toxin type A interacts with the sweat glands. Sweating is triggered when nerves release acetylcholine, a chemical messenger, onto the eccrine glands in the skin. Botulinum toxin type A temporarily blocks this release, so the glands stop being activated in the treated area. In the palm, the doctor injects many tiny doses just under the surface, often across a grid of 30 to 50 points per palm, because sweat glands are spread evenly and each injection covers only a small radius. This shallow, distributed technique is what produces the even, dry before-and-after across the whole palm rather than patchy relief. Because the palm is sensitive, comfort measures such as a topical numbing cream, cooling, or a nerve block are commonly used. The effect is not immediate or permanent: sweating typically drops within 2 to 7 days as the blocked signal takes hold, and returns gradually over about 4 to 6 months as nerve endings recover, which is why the treatment is repeated to maintain the result rather than done once.
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The clinic’s doctors gauge how much each palm sweats and mark a grid of roughly 30 to 50 injection points per palm.
Because palms are sensitive, numbing cream, cooling, or a nerve block is used for about 15 to 30 minutes before injecting.
Small doses, often 1.5 to 2 units per point, are placed shallowly across each palm to block sweat-gland activation.
Sweating usually drops within 2 to 7 days, with the full dry before-and-after effect settling by about 1 week.
As the effect fades over roughly 4 to 6 months, a maintenance session restores the dry result.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
The clinic’s doctors assess how much your palms sweat, explain a realistic before-and-after, and answer your questions in English.
After about 15 to 30 minutes of numbing, the grid of injections across both palms usually takes around 20 to 30 minutes.
The dry result is not instant; sweating drops over about 2 to 7 days, with the full effect settling by around 1 week.
Palms typically stay comfortably dry for about 4 to 6 months, and your doctor can review how evenly the effect took.
As sweating returns over 4 to 6 months, a repeat session restores dryness, which international patients often plan around future trips.
Before treatment, palms are often damp or dripping; after intradermal botulinum toxin type A, most patients have dry, comfortable palms within about 1 week. The change typically lasts 4 to 6 months. You can read the wider approach on our botox injection page before your consultation.
Sweating usually starts to drop within 2 to 7 days, and the full dry result settles by about 1 week, not immediately. This gradual onset is normal as the blocked nerve signal takes effect, as explained on our botox injection page. Your doctor reviews how evenly your palms responded.
For most patients, palms stay comfortably dry for about 4 to 6 months before sweating gradually returns, so it is maintained rather than a one-time fix. A repeat session restores the effect. Your doctor explains a suitable maintenance rhythm based on how quickly your sweating comes back.
The palm is sensitive, so many small injections can sting, but comfort measures make it manageable. Numbing cream, cooling, or a nerve block is used for about 15 to 30 minutes beforehand. Most patients tolerate the grid of injections well and describe the discomfort as brief and worth the relief.
Each palm usually receives a grid of roughly 30 to 50 shallow injections, because sweat glands are spread evenly and each dose covers only a small area. This distribution is what creates the even, dry before-and-after. Your doctor maps the grid to the size of your palm and where you sweat most.
Most adults with moderate to severe primary palmar sweating are suitable, especially when antiperspirants have not been enough. A consultation confirms your suitability and rules out other causes. Conditions like pregnancy or certain neuromuscular disorders mean it is not advised, which your doctor reviews on our injection treatment page first.
Studies report no lasting loss of grip strength from correctly placed intradermal dosing, though some patients notice mild, temporary hand weakness for a short time. This usually settles within a couple of weeks. Your doctor uses shallow, targeted placement to focus on sweat glands rather than the deeper hand muscles.
Downtime is minimal, so most patients return to normal activities the same day. Palms may be slightly tender or show tiny marks that settle within hours. Avoid heavy gripping, intense heat, or vigorous hand use for the rest of the day, as your doctor will explain during the visit.
Botulinum toxin for sweaty palms is widely performed and generally considered safe when a trained doctor uses appropriate dosing and technique. A consultation reduces risks such as temporary tenderness or brief hand weakness. You can review the broader approach on our injection treatment page before booking.
Most side effects are mild and short-lived: tenderness, small bruises, or brief redness at the injection points. Some patients notice temporary, mild hand weakness that resolves within a couple of weeks. Serious effects are uncommon. Your doctor discusses these possibilities before you decide to proceed with treatment.
Botulinum toxin offers months of even dryness from one visit, while prescription antiperspirants need daily use and iontophoresis needs frequent home sessions. Each suits different severities. Your doctor helps you weigh these options at consultation, and lighter cases may combine them with a supportive skin care routine.
One session produces the dry before-and-after, and most patients then repeat every 4 to 6 months as sweating returns. Some schedule it seasonally, such as before summer. The exact interval depends on how quickly your palms sweat again, which your doctor reviews to keep your plan efficient.
Aftercare is simple: avoid heavy gripping, hot water, and vigorous hand activity for the rest of the day, and keep the palms clean. Tiny marks settle quickly. Moisturising and gentle care help the skin recover. Your doctor gives tailored aftercare so the even dry result develops smoothly over the first week.
For a first session, 1 day in Seoul is usually enough, covering the consultation and the injections. Because the dry effect builds over about a week, most international patients fly home the same trip. Our English-speaking team helps schedule the visit around your travel and other plans.
Yes, flying within a day is generally fine, as palm hyperhidrosis treatment is minimally invasive with only tiny injection points. Avoid heavy gripping and very hot water for a day. The dry result continues to develop over the week, and your doctor will advise on aftercare to follow while you travel.
International patients can plan repeat sessions around return trips, and the clinic offers remote check-ins in English between visits so your plan stays on track. Between treatments, a supportive skin care routine helps. Your treatment notes are kept on file for consistent dosing across visits.
| Botulinum Toxin Injection | Prescription Antiperspirant | Iontophoresis Device | |
|---|---|---|---|
| Mechanism | Blocks nerve signals to palm sweat glands | Aluminium salts plug sweat ducts topically | Mild electrical current passed through water |
| Best for | Moderate to severe sweaty palms wanting a clear change | Mild sweating or between other treatments | Those preferring an at-home, device-based routine |
| Onset | Dryness within about 1 week | Gradual, with consistent nightly use | Builds over several sessions |
| Comfort | Multiple injections, eased with numbing | Can cause skin irritation | Tingling during each session |
| Longevity | Typically 4 to 6 months per session | Only while used regularly | Requires ongoing maintenance sessions |
| Effort | One clinic visit, then repeat seasonally | Daily topical routine | Frequent repeated home sessions |
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