Gangnam
Dr. Yoon-Gon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)
Rejuran HB is a hybrid of polynucleotide (PN) and hyaluronic acid, and split-face studies report improved hydration and elasticity over a series of about 3 sessions spaced 2 to 4 weeks apart.
To choose a good Rejuran HB clinic in Seoul, Korea, look for doctor-led injection, honest expectations, and a plan built around a series of about 3 sessions. Rejuran HB combines polynucleotide with hyaluronic acid to hydrate and improve skin quality. Reberry Clinic assesses your skin at its Seoul locations and tailors depth and dosing in clear English.
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Rejuran HB (Hydro Booster) is an injectable skin booster that combines polynucleotide (PN, salmon-derived DNA fragments) with hyaluronic acid (HA). The polynucleotide component is a regenerative biostimulator that supports fibroblast activity and skin quality, while the added hyaluronic acid provides immediate hydration and plumping. This hybrid makes Rejuran HB a hydration-focused member of the Rejuran family, aimed at dewy, healthier-looking skin rather than volumising or lifting.
It is injected intradermally across the face in a series, most often about 3 sessions spaced 2 to 4 weeks apart, so improvements in hydration, elasticity, and fine-line texture build over time. Because a top-rated label is a subjective claim no clinic can honestly guarantee, a more useful question is how to choose a good clinic: one where a doctor performs the injections, assesses your skin type and goals first, and sets realistic expectations across the course.
Reberry Clinic is a Seoul dermatology and aesthetic clinic supporting international patients in English. Rejuran HB here is consultation-led: the clinic’s doctors at our operating Seoul locations in Gangnam and Myeongdong evaluate your skin, tailor injection depth and dosing, and explain the plan and cost transparently before you start.
Rejuran HB relies on two complementary mechanisms. The polynucleotide fraction consists of purified DNA fragments that act as a biostimulator: once placed in the dermis, they support fibroblast activity, aid tissue repair, and are associated with improved skin elasticity and texture over successive sessions rather than an instant change. The hyaluronic acid fraction is a hydrophilic molecule that binds water, giving more immediate hydration and a plumped, dewy surface. Because the HA is typically non-crosslinked and lighter than a volumising filler, Rejuran HB improves skin quality across an area instead of building contour. The two are delivered together through fine intradermal injections, often with a series of micro-injections across the face; a good clinic tailors depth, spacing, and number of points to your skin, which is why a doctor-led assessment matters more than any single marketing claim.
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The doctor evaluates hydration, elasticity, and goals to confirm Rejuran HB fits, and plans the series of about 3 sessions.
The area is cleansed and numbing cream is applied for around 20 to 30 minutes to keep the injections comfortable.
The PN plus HA blend is placed through fine micro-injections across the face; a session typically takes about 20 to 30 minutes.
HA hydrates within days, while the polynucleotide effect on skin quality builds across the 2 to 4 week gaps between sessions.
Most plans run about 3 sessions, and the doctor reviews response before advising on maintenance every few months.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
The clinic’s doctors at our Seoul locations assess your skin, confirm Rejuran HB fits, and explain the plan and cost in English.
After numbing for about 20 to 30 minutes, the injection session usually takes another 20 to 30 minutes.
Rejuran HB is a course, so plans typically run about 3 sessions spaced 2 to 4 weeks apart rather than a single visit.
Hydration is noticeable within days, while improvements in elasticity and texture build across the series over several weeks.
Results are maintained with periodic sessions every few months, plus good sun protection and a supportive skincare routine.
Look for a clinic where a doctor performs the injections, assesses your skin type and goals first, sets realistic expectations across a series of about 3 sessions, and explains cost transparently. Avoid claims that sound too perfect. At our Seoul locations, the clinic’s doctors tailor depth and dosing to your skin in English.
Rejuran HB combines polynucleotide with added hyaluronic acid, so it hydrates as well as supporting skin quality, while classic Rejuran Healer is polynucleotide-focused for regeneration and texture. HB suits dehydrated, dull skin wanting both effects. You can compare related boosters on our Rejuran Healer page before deciding.
Rejuran HB is available at Reberry Clinic’s operating Seoul locations in Gangnam and Myeongdong, with the clinic’s doctors leading treatment and English support for international patients. A consultation confirms whether Rejuran HB or another injection treatment best fits your skin goals.
Most patients find it well tolerated because numbing cream is applied for about 20 to 30 minutes before the micro-injections. You may feel small pinches and brief stinging as the product goes in. Temporary tiny bumps, redness, or mild bruising afterward are common and usually settle within a few days, which your doctor reviews with you.
Most plans run about 3 sessions spaced 2 to 4 weeks apart, so skin quality can build between visits, rather than a single treatment. The exact number depends on your skin condition and goals. Your doctor reviews response across the series and advises on maintenance sessions every few months to sustain results.
Hydration and a dewier surface are often noticeable within days thanks to the hyaluronic acid, while improvements in elasticity and texture from the polynucleotide build gradually over the series across several weeks. Because it is regenerative, the fuller effect appears over the course rather than immediately after the first session.
Results typically last several months and are maintained with periodic sessions rather than being a one-time fix, since skin quality naturally changes over time. Sun protection and a good skin care routine help prolong the effect. Your doctor recommends a maintenance interval, often every few months, based on your skin.
Downtime is usually minimal. Small injection bumps, redness, or mild bruising can appear and generally settle within a few days as the hyaluronic acid disperses. Avoid heavy makeup, saunas, and intense exercise for a day or so. Your doctor gives aftercare so you can plan around any short-lived marks, especially before events.
Yes, Rejuran HB is often combined with energy-based skin tightening or other boosters in a staged plan for broader results, once your skin has settled. Sequencing matters to avoid over-treating. Your doctor may pair it with a supportive skin care routine and space other procedures appropriately across your plan.
Rejuran HB is a skin booster, not a volumising filler. It improves hydration and skin quality across an area rather than building contour or lift, because its hyaluronic acid is lighter and non-crosslinked. If you want structural volume, a different treatment is more suitable, which your doctor explains when matching the option to your goals.
Adults with dull, dehydrated skin who want improved hydration and skin quality, rather than volume or lifting, are typically good candidates. A consultation checks your skin condition, goals, and any allergies, including to salmon-derived components. Pregnancy, active skin infection, or certain medical conditions may mean deferring treatment, which your doctor reviews upfront.
Common effects are temporary injection bumps, redness, swelling, mild bruising, and short-lived tenderness, which usually resolve within days. Allergic reactions are uncommon but possible, so salmon-DNA allergy is checked first. Serious complications are rare with doctor-led injection. Your doctor reviews your history and aftercare to keep the treatment as safe as possible for your skin.
Cost depends on the number of sessions, the area treated, and the product volume used, so there is no single fixed price. Because plans are individualised across a series, the clinic’s doctors confirm your cost transparently at consultation rather than quoting one figure for everyone, and explain what your plan includes.
A pure hyaluronic acid booster mainly hydrates and adds glow, while Rejuran HB adds polynucleotide for a regenerative effect on elasticity and texture on top of hydration. So HB targets both skin quality and a glass-skin glow. Your doctor helps you compare them to match the booster to your priorities.
For a single session, 1 to 2 days is enough, allowing a consultation, the treatment, and time for any short-lived redness to settle. Because Rejuran HB runs as a course, many international patients begin in Seoul and plan return visits for later sessions. Our English-speaking team helps schedule around your travel.
Yes, flying within a day or so is generally fine, as Rejuran HB is a minimally invasive injectable. Cabin air is drying, so keep skin moisturised and protect it from sun. Avoid heavy makeup over injection points for the first day. Your doctor gives aftercare so travel does not affect your results.
International patients can complete the series across one or more visits, and the clinic offers remote check-ins in English between trips so your plan and maintenance stay on track. You can also continue a supportive skin care routine at home. Your treatment notes are kept on file for continuity.
| Rejuran HB | Rejuran Healer | HA Skin Booster | |
|---|---|---|---|
| Composition | Polynucleotide plus hyaluronic acid hybrid | Polynucleotide (PN) focused | Hyaluronic acid focused |
| Main aim | Hydration plus skin-quality regeneration | Skin regeneration and texture | Primarily hydration and glow |
| Best for | Dull, dehydrated skin wanting both effects | Skin repair and elasticity focus | A quick hydration and dewiness boost |
| Sessions | Usually about 3, spaced 2 to 4 weeks apart | Usually about 3 to 4 in a series | Often a short series then maintenance |
| Onset | Hydration early, skin quality builds over weeks | Builds gradually over the series | Hydration relatively early |
| Cost factors | Depends on sessions, area, and product volume | Depends on sessions and area | Depends on sessions and area |
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