Gangnam
Dr. Yoon-Gon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)
Rejuran HB combines polynucleotide (PN) with hyaluronic acid; a typical plan is about 3 to 4 sessions spaced 2 to 4 weeks apart for hydration plus skin repair.
Rejuran HB in Korea usually needs a course of about 3 to 4 sessions spaced 2 to 4 weeks apart. Because it blends polynucleotide (PN) skin repair with added hyaluronic acid for hydration, each session compounds the effect, so the improvement in glow, texture, and elasticity builds across the course rather than appearing fully after one visit.
One-on-One guidance from a dedicated doctor, ensuring your skin is professionally monitored and treated from start to finish.
Fluent assistance in English, Japanese, and Chinese, making communication clear, respectful and comfortable for international patients.
Over 100,000 patients worldwide have received our personalized dermatological care, highlighting our expertise and reliable results.
Rejuran HB is the polynucleotide (PN) skin booster that adds hyaluronic acid, pairing salmon-DNA skin repair with immediate hydration in one injectable. Because it works partly by stimulating your own collagen, it is planned as a course rather than a single visit: most patients need about 3 to 4 sessions spaced 2 to 4 weeks apart to reach the full effect. The added hyaluronic acid gives an earlier hydration lift, while the polynucleotide component keeps building elasticity and texture across the course.
The exact number is individual. Skin that is thin, dull, dehydrated, or more mature may benefit from 4 sessions, while skin in better baseline condition may do well with about 3. After the initial course, most patients maintain their result with a single top-up session every few months. Your treatment goal, whether hydration-led glow or deeper skin repair, also shapes how many sessions your doctor recommends.
For international patients, Rejuran HB is a signature reason to visit Seoul, where the Rejuran range originated. Reberry Clinic serves visitors across three Seoul-area locations (Gangnam, Myeongdong, Incheon Airport), with English-language consultation and treatment planned and reviewed by the clinic’s doctors, who tailor the session count to your skin and travel schedule.
Rejuran HB combines polynucleotides, high-molecular-weight DNA fragments purified from salmon milt and processed to remove proteins for biocompatibility, with hyaluronic acid for hydration. When micro-injected into the dermis, the polynucleotide chains form a temporary scaffold that signals fibroblasts to make new collagen, while the hyaluronic acid holds water for an earlier glow. Collagen builds gradually over weeks, which is why a single session cannot deliver the full effect and why the treatment is planned across about 3 to 4 sessions. Each visit adds to the collagen laid down before, so spacing sessions 2 to 4 weeks apart lets the repair compound while the hydration keeps skin looking fresh in between.
One Reberry Clinic, multiple Seoul-area locations. Pricing & current promotions are listed on each branch's own site — tap a clinic to view pricing & book.
ONE REBERRY CLINIC · MFDS-REGISTERED DEVICES · MULTILINGUAL CARE AT EVERY LOCATION
The clinic’s doctors assess your skin and recommend a plan, typically 3 to 4 sessions for a full course.
After numbing for 20 to 30 minutes, the micro-injection takes about 15 to 20 minutes and adds early hydration.
Sessions are spaced 2 to 4 weeks apart so collagen can build between each visit.
Across the 3 to 4 sessions, elasticity, texture, and glow accumulate as new collagen forms.
After the course, a single top-up session every few months sustains the result.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
The clinic’s doctors assess your skin, discuss goals, and recommend a course of about 3 to 4 sessions, explained in English.
After numbing, each micro-injection session takes about 15 to 20 minutes, with the visit under an hour.
A full course runs across about 3 to 4 sessions spaced 2 to 4 weeks apart.
Hydration shows early, while elasticity and texture build over the weeks of the course.
Results last several months; a single top-up every few months, plus sun care, maintains them.
Most patients need a course of about 3 to 4 sessions spaced 2 to 4 weeks apart for the full Rejuran HB effect. The polynucleotide component builds collagen gradually, so each session compounds the last. Your exact number depends on skin condition and goals, confirmed at consultation. Our Rejuran page explains how the course is planned.
One session gives early hydration from the hyaluronic acid but does not build the full collagen reserve, so the repair effect stays partial. Rejuran HB is designed as a course of about 3 to 4 sessions where each visit adds to the last. The cumulative collagen across the course is what delivers lasting elasticity and texture improvement.
Sessions are usually spaced 2 to 4 weeks apart, which lets new collagen build between visits while the added hydration keeps skin looking fresh. Spacing that is too tight does not give the skin time to respond. Your doctor sets the interval to fit both your skin’s healing and your travel schedule if you are visiting Seoul.
Baseline skin quality, age, hydration, and your goal decide the number. Thin, dull, dehydrated, or more mature skin often benefits from 4 sessions, while skin in better condition may do well with about 3. Your doctor assesses your skin at consultation and adjusts the plan, adding a session if your skin needs more repair.
Rejuran HB adds hyaluronic acid to the polynucleotide for an earlier hydration lift, while Rejuran Healer focuses purely on skin repair and quality. Both use the same salmon-DNA technology and similar session counts. Your doctor selects the right one for your goals; our Rejuran Healer page explains the repair-focused option in detail.
Most patients feel mild stinging during the micro-injections, well managed with topical numbing applied for 20 to 30 minutes beforehand. Each injection phase lasts only 15 to 20 minutes. The added hyaluronic acid can make the gel feel slightly fuller going in, but discomfort is brief and fine needles keep each session comfortable throughout.
Downtime is minimal: small raised bumps and mild redness at the injection points typically settle within one to two days, so they resolve well before your next session 2 to 4 weeks later. Occasional light bruising can occur. Most international visitors resume gentle sightseeing the following day and cover any residual redness with light makeup.
Hydration from the hyaluronic acid shows within days, while the polynucleotide repair builds gradually over the weeks of the course. Many patients notice smoother, more elastic skin after the second session, with the fullest effect after the final one. Clinical studies measured significant elasticity gains by 12 weeks, reflecting this progressive build-up.
Results commonly last several months after the full course, after which a single top-up session every few months helps sustain them. Because Rejuran HB supports your own repair, natural ageing continues, so it is not a one-time fix. Pairing it with a consistent skin care routine helps extend the benefit.
Yes, Rejuran HB is often combined with lasers, energy lifting, or other boosters, sequenced safely by your doctor across your sessions. Many patients add a glow-focused treatment for extra radiance. You can compare a hydration-led option on our glass-skin booster page to see how it fits alongside your course.
Yes, once the initial course of about 3 to 4 sessions is complete, maintenance usually needs just a single visit every few months. This refreshes collagen and hydration without repeating the full course. A steady skin care routine helps you stretch the interval between maintenance visits.
Yes, Rejuran HB has a well-documented safety profile and is designed for a repeated course, with the purified polynucleotide processed to remove proteins for biocompatibility. Side effects are usually limited to temporary redness or small bumps. Your doctor reviews your history, including any salmon allergy, before starting the course to keep repeat sessions safe.
Expect temporary redness, mild swelling, small bumps at injection points, and occasional light bruising for a day or two after each session, all resolving on their own. Less common reactions include tenderness or transient itching. Serious complications are rare when an experienced doctor injects using correct technique and sterile conditions throughout the course.
Aftercare is simple: keep the area clean, avoid makeup for the rest of the day, and skip saunas, intense exercise, and alcohol for a couple of days after each session. Protect skin from sun and stay hydrated. Your clinic provides written aftercare so you can follow the routine confidently between sessions and after you travel home.
For a single Rejuran HB session you need only one to two days, covering consultation and treatment with minimal downtime. Because the full course spans several weeks, most international patients complete part of it during their stay and arrange the remaining sessions on a return trip. Our English team coordinates the schedule around your travel.
Flying the next day is generally fine, and if you cannot complete every session in Seoul, your team helps plan the remaining visits for a return trip and offers remote check-ins in English between them. You can also explore related care such as glass-skin boosters. Your treatment notes stay on file for continuity.
| Rejuran HB (PN+HA) | Rejuran Healer | Skin booster (HA) | |
|---|---|---|---|
| Active / mechanism | Polynucleotide plus hyaluronic acid, repair and hydration | Polynucleotide (PN, salmon DNA), skin-healing repair | Hyaluronic acid micro-droplets, hydration |
| Typical course | About 3 to 4 sessions | About 3 sessions | Often a short series |
| Spacing | 2 to 4 weeks apart | 2 to 4 weeks apart | Varies, often 2 to 4 weeks |
| Best for | Repair plus early hydration and glow | Overall skin quality, elasticity, texture | Deep hydration and glow |
| Onset of results | Early hydration, repair builds over weeks | Gradual over weeks across the course | Hydration within days, refines over weeks |
| Downtime | Tiny bumps and redness for a day or two | Tiny bumps and redness for a day or two | Minimal, brief redness |
| Maintenance | Single visit every few months | Single visit every few months | Periodic, varies |
| Cost context | Consultation-led; depends on sessions and area | Consultation-led; depends on sessions and area | Consultation-led; depends on product and area |
Real verified reviews from our Google Business Profile, across all Reberry Clinic locations.
PULLED LIVE FROM GOOGLE · GANGNAM · MYEONGDONG · INCHEON AIRPORT
Your treatment is planned and performed by experienced, MFDS-registered doctors across our Seoul-area clinics, with multilingual support for international patients.
Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)
Multilingual tourist care beside Myeongdong Cathedral
Fast, effective care 20 minutes from the terminals
Message us on WhatsApp for a free consultation in English about how many Rejuran HB sessions suit your skin.