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Hyperhidrosis Treatment near Hongdae, Seoul, Korea

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Botulinum toxin blocks the nerve signals that switch on your sweat glands, with most patients staying noticeably drier for around 4 to 9 months per session.

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Hyperhidrosis treatment uses botulinum toxin injected into the skin of overactive areas, such as the underarms, palms, or soles, to block the nerve signals that trigger sweat glands. Most patients stay noticeably drier for about 4 to 9 months per session. For patients near Hongdae (Hongik Univ.) Station, care is provided at our Seoul locations with full English support.

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What is hyperhidrosis treatment with botulinum toxin?

Hyperhidrosis is excessive sweating beyond what the body needs to regulate temperature, most often affecting the underarms, palms, soles, and sometimes the forehead. Botulinum toxin treatment addresses it directly at the source: small amounts of botulinum toxin type A are injected just under the skin of the overactive area, where they temporarily block the nerve signals that tell sweat glands to produce sweat. Because it targets the local nerve-to-gland pathway rather than the whole body, sweating in the treated area drops sharply while the rest of your body regulates temperature normally.

Primary focal hyperhidrosis affects roughly 1 to 3 percent of the population and often starts in adolescence, and studies show it meaningfully lowers quality of life through social, work, and clothing concerns. Botulinum toxin is a widely used, non-surgical option for moderate to severe cases that have not responded to prescription antiperspirants. A typical underarm session takes about 15 to 30 minutes, most patients notice dryness within 2 to 7 days, and the effect commonly lasts 4 to 9 months before a repeat session is considered.

At Reberry Clinic, hyperhidrosis care is consultation-led: the clinic’s doctors map your active sweat zones, confirm the diagnosis, and plan dosing per area in English. For international patients near Hongdae (Hongik Univ.) Station, this care is provided across our Seoul locations (Gangnam, Myeongdong), easily reached from 홍대입구역.

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How botulinum toxin stops excess sweating

Sweat glands are switched on by a chemical messenger called acetylcholine, released by tiny nerve endings around each gland. Botulinum toxin type A works by temporarily preventing those nerve endings from releasing acetylcholine, so the signal to sweat never reaches the gland. The gland is not removed or damaged; it simply receives no instruction to activate, which is why sweating in the treated zone falls dramatically while temperature control elsewhere is unaffected. A grid of shallow micro-injections spaced roughly 1 to 2 cm apart covers the active area evenly, typically 10 to 20 points per underarm. Because the effect is local and the nerve endings gradually regenerate over months, results are temporary and repeatable rather than permanent, and the same approach can be applied to palms and soles with appropriate comfort measures. The clinic’s doctors adjust the number of units and injection points to the size of your active zone and the severity mapped at consultation, which is why dosing is individualised rather than fixed.

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Key Benefits

Key Benefits

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How It Works

How Hyperhidrosis Treatment Works

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Map the active zone

A starch-iodine test or clinical assessment outlines exactly where sweating is heaviest, guiding a grid of about 10 to 20 injection points per underarm.

For palms and soles, topical numbing or cooling is used first, since these zones are more sensitive than the 2 underarms.

Botulinum toxin type A is placed just under the skin at points spaced roughly 1 to 2 cm apart, delivering a small, even dose across the mapped area.

Sweating begins to fall within 2 to 7 days as the treated nerve endings stop signalling the sweat glands.

Relief commonly lasts about 4 to 9 months, after which a repeat session restores the effect as nerve endings regenerate.

Comparison

Hyperhidrosis Options Compared

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Before & After

Real Before & After Results

See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.

Botox Injection before and after result 1 at Reberry Clinic
Botox Injection — result 1
Botox Injection before and after result 2 at Reberry Clinic
Botox Injection — result 2
Botox Injection before and after result 3 at Reberry Clinic
Botox Injection — result 3
Botox Injection before and after result 4 at Reberry Clinic
Botox Injection — result 4
Botox Injection before and after result 5 at Reberry Clinic
Botox Injection — result 5
Results vary by individual. Photos taken under standardized clinical lighting at Reberry Clinic during the 90–180 day post-treatment window.
The Process

Your Hyperhidrosis Treatment Journey

Consultation

The clinic’s doctors confirm the diagnosis, map your active sweat zones, and plan the dose per area in English, then explain what drives the cost.

An underarm session usually takes about 15 to 30 minutes; palms and soles are numbed first as they are more sensitive.

Most patients notice dryness within 2 to 7 days, with the effect building over the first 2 weeks.

Peak dryness settles within about 2 weeks and commonly lasts 4 to 9 months per session.

Because nerve endings regenerate over months, repeat sessions maintain results; avoid rubbing or heat on the area for 24 hours.

Good Candidates

Cautions & Contraindications

Scientific Evidence

Randomized and prospective studies consistently show botulinum toxin type A reduces focal sweating and improves quality of life. In a placebo-controlled trial in severe axillary hyperhidrosis, a large majority of treated patients achieved a substantial reduction in sweat production versus placebo. A one-year prospective study reported sweat output falling from about 0.81 g to 0.23 g per 15 minutes, Hyperhidrosis Disease Severity Scale scores dropping from roughly 3.4 to 1.5, and Dermatology Life Quality Index scores improving from about 19.9 to 6.9. Reported duration of effect commonly ranges from 4 to 9 months, and comparative trials position botulinum toxin against energy-based and microneedle-radiofrequency alternatives.
  • Naumann M, Lowe NJ. Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial. BMJ. 2001;323(7313):596-599. doi:10.1136/bmj.323.7313.596
  • Vadeboncoeur S, et al. Assessing botulinum toxin effectiveness and quality of life in axillary hyperhidrosis: a one-year prospective study. Diseases. 2024;12(1):15. doi:10.3390/diseases12010015
  • Rystedt A, et al. Randomized controlled trial comparing the efficacy and safety of two injection techniques of incobotulinumtoxinA for axillary hyperhidrosis. J Drugs Dermatol. 2020;19(8):765-772. doi:10.36849/JDD.2020.4989
  • Elshahed AR, et al. Long-term efficacy of fractional microneedle radiofrequency versus botulinum toxin-A in primary axillary hyperhidrosis: a randomized controlled trial. Lasers Med Sci. 2024;39(1):182. doi:10.1007/s10103-024-04115-x
  • Nasr MW, et al. Botulinum toxin A versus microwave thermolysis for primary axillary hyperhidrosis: a randomized controlled trial. JAAD Int. 2024;15:35-41. doi:10.1016/j.jdin.2023.12.011
  • Naumann M, et al. Botulinum toxin type A is a safe and effective treatment for axillary hyperhidrosis over 16 months. Arch Dermatol. 2003;139(6):731-736. doi:10.1001/archderm.139.6.731
FAQ

Frequently Asked Questions

What is hyperhidrosis treatment with botulinum toxin?

It is a non-surgical procedure where small amounts of botulinum toxin type A are injected just under the skin of overactive areas to block the nerve signals that trigger sweat glands. Sweating in the treated zone drops sharply, while your body still regulates temperature normally elsewhere, usually for several months per session.

Botulinum toxin blocks the release of acetylcholine, the chemical messenger that tells sweat glands to activate. Without that signal, treated glands stay quiet, so sweating falls dramatically in the area. The gland itself is not removed, which is why the effect is temporary and wears off over 4 to 9 months as nerve endings recover.

The most common areas are the underarms, palms, and soles, and sometimes the forehead or scalp. Underarms are the most frequently treated and the most comfortable. Palms and soles are more sensitive, so numbing or cooling is used first. Your doctor confirms which zones are active and suitable during your botox injection consultation.

Underarm treatment is generally well tolerated with fine needles and takes about 15 to 30 minutes. Palms and soles are more sensitive, so topical numbing or cooling is applied first to keep you comfortable. Most patients describe brief pinpricks rather than significant pain, and no recovery time is needed afterward.

Most patients notice sweating begin to fall within 2 to 7 days, with the full effect settling over about 2 weeks. The onset reflects how quickly the botulinum toxin blocks the nerve signals to your sweat glands. Your doctor may review the result at around 2 weeks to confirm even coverage of the treated zone.

Relief commonly lasts about 4 to 9 months per session, though this varies by person and treated area. Underarms often hold longer than palms. Because nerve endings gradually regenerate, sweating slowly returns and a repeat session restores dryness. Many patients plan sessions once or twice a year to stay comfortable.

Underarms typically need about 10 to 20 small injections each, spaced roughly 1 to 2 cm apart across the mapped active zone. Palms and soles vary with hand and foot size. Your doctor maps the sweating area first, often with a starch-iodine test, so the grid covers only where you actually sweat heavily.

Compensatory sweating in other areas is uncommon with botulinum toxin because the treatment is localized to the injected zone, unlike surgery that cuts sweat nerves. Your body continues to regulate temperature normally through untreated areas. Any minor changes are typically mild and were discussed at consultation before your session.

Botulinum toxin for focal hyperhidrosis is widely performed and generally considered safe when dosed and placed by a trained doctor. Studies report high satisfaction and meaningful quality-of-life gains. Temporary tenderness or minor bruising can occur. A consultation screens for contraindications first; you can read our approach on the botox injection page.

Prescription antiperspirants are a lower-cost first step but must be used continuously, while botulinum toxin blocks the sweat signal for months. Energy devices aim for longer-lasting change but involve more downtime. If your sweating overlaps with skin concerns, our laser treatment options can be discussed at the same consultation.

Aftercare is simple: avoid rubbing, heat, saunas, and intense exercise on the treated area for about 24 hours, and skip shaving underarms that day. There is little to no downtime, so most people return to work immediately. Your doctor gives tailored guidance and a review timeline before you leave the clinic.

Yes, hyperhidrosis injections can often be scheduled alongside other aesthetic or skin treatments during the same visit, depending on the areas involved. Many international patients coordinate several treatments per trip. Your doctor sequences them so the skin is not over-stressed, and can outline options such as a skin care plan for overall skin health.

Most adults with moderate to severe focal sweating that persists despite antiperspirants are suitable candidates. A consultation confirms the diagnosis and rules out contraindications such as pregnancy or certain neuromuscular conditions. Your doctor maps the active zones and explains options on our injection treatment page before you start.

Cost depends on how many zones are treated and the number of units needed to cover your active sweating area, since underarms, palms, and soles differ in size. Because plans are individualised, the clinic’s doctors confirm your cost at consultation rather than quoting one fixed figure. You can start on the botox injection page.

Patients near Hongdae (Hongik Univ.) Station are cared for at our Seoul locations in Gangnam and Myeongdong, both easily reached from 홍대입구역 by subway. Our English-speaking team helps you choose the most convenient location and coordinate your appointment, so travel from the Hongdae area is straightforward for international patients.

A single day is usually enough for hyperhidrosis injections, since a session takes about 15 to 30 minutes with little downtime. Some patients add a day for a review or to combine other treatments. Our English-speaking team helps schedule your visit efficiently around your travel plans from Seoul.

Yes, flying within a day is generally fine because hyperhidrosis injections are minimally invasive with little downtime. Simply avoid heat, saunas, and rubbing the treated area for about 24 hours. Full dryness develops over the following 2 weeks, so you will continue to see improvement after you return home.

International patients can complete a session in a single visit, and the clinic offers remote check-ins in English if you have questions as the effect settles over 2 weeks. Because results last months, many patients simply plan a repeat session on a future trip. Your treatment notes are kept on file for continuity.

Botulinum ToxinPrescription AntiperspirantsMicrowave / Energy Device
MechanismBlocks nerve signals to sweat glandsAluminium salts plug sweat ducts topicallyHeat energy reduces underarm sweat glands
Best forModerate to severe focal sweatingMild sweating or first-line trialUnderarm sweating seeking longer-lasting change
OnsetDryness within 2 to 7 daysGradual over 1 to 2 weeks of useReduction over weeks after sessions
DowntimeLittle to noneNone, but can irritate skinSwelling and soreness for several days
DurationAbout 4 to 9 months per sessionOnly while used regularlyLonger-lasting, often 1 to 2 sessions
Areas treatedUnderarms, palms, solesMainly underarmsUnderarms only
Cost contextDepends on units and number of zonesLower per unit but ongoingHigher upfront, device-based
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Our Doctors

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Dr. Yoongon Ryu — Aesthetic Medicine Specialist, Reberry Clinic Gangnam
Gangnam

Dr. Yoongon Ryu

Aesthetic Medicine Specialist

Flagship clinic · KOL for leading lifting & regenerative devices

Dr. Seung Jae Baek — Medical Director, Reberry Clinic Myeongdong
Myeongdong

Dr. Seung Jae Baek

Medical Director

Multilingual tourist care beside Myeongdong Cathedral

Dr. Seongjun Cho — Aesthetic Medicine Specialist, Reberry Clinic Incheon Airport
Incheon Airport

Dr. Seongjun Cho

Aesthetic Medicine Specialist

Fast, effective care 20 minutes from the terminals

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