Gangnam
Dr. Yoon-Gon Ryu
Aesthetic Medicine Specialist
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Botulinum toxin type A blocks the nerve signals to sweat glands in the palms, with relief that typically lasts around 6 months per session.
Palm hyperhidrosis, or excessive sweating of the hands, is treated in Gangnam, Seoul with botulinum toxin type A injected across the palm to block the nerve signals that trigger sweat glands. Relief usually begins within a week and lasts around 6 months per session, letting you grip, write, and shake hands without constantly wet palms.
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Palm hyperhidrosis is excessive, uncontrollable sweating of the hands that goes beyond what the body needs for temperature regulation. It is a common form of primary focal hyperhidrosis, meaning the sweating has no underlying medical cause and is driven by overactive nerve signals to the sweat glands in the palms. For many people it starts in adolescence and continues for years, affecting handwriting, gripping objects, using touchscreens, and simple social moments like shaking hands.
Botulinum toxin type A is a well-established treatment for sweaty palms. Injected in small amounts across the palm, it temporarily blocks the chemical messenger that tells sweat glands to activate, dramatically reducing sweat production in the treated area. Unlike antiperspirants, which sit on the surface, the toxin works at the nerve-to-gland signal itself, which is why the effect is both stronger and longer lasting for focal sweating.
At Reberry Clinic, palm hyperhidrosis treatment is consultation-led at our Gangnam (Seoul) location, about 2 minutes from Gangnam Station exit 10, with Dr. Yoongon Ryu and full English support. Because palm injections can be sensitive, the clinic’s doctors discuss comfort measures and map the treatment area carefully before starting.
Sweat glands are switched on by acetylcholine, a chemical messenger released by nerve endings. In palm hyperhidrosis, these signals fire excessively, so the glands overproduce sweat. Botulinum toxin type A works by temporarily blocking the release of acetylcholine at those nerve endings, which interrupts the signal and sharply reduces sweating in the injected zone. The treatment is delivered as a grid of small, shallow intradermal injections spaced across the palm, typically 15 to 25 points per hand, so the toxin covers the sweat-gland field evenly. Because the palm is a sensitive area with many nerve endings, comfort measures such as topical numbing, cooling, or a nerve block are used to make the session tolerable. The effect is local: only sweat production in the treated area is reduced, and normal hand strength and sensation are preserved, though a small, temporary reduction in grip strength is occasionally reported and resolves on its own. As the toxin gradually wears off over roughly 6 months, sweating returns, so repeat sessions maintain the result.
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A doctor confirms primary palm hyperhidrosis and rules out secondary causes, since about 90% of focal cases are primary.
Comfort measures such as topical numbing, cooling, or a nerve block are applied before the 15 to 25 injection points.
The doctor marks a grid across each palm so the toxin is spread evenly over the sweat-gland field.
Small intradermal doses of botulinum toxin type A are placed at each of the roughly 15 to 25 points per hand.
Sweat production falls noticeably within about 1 week, with the effect lasting around 6 months before a repeat session.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
A doctor confirms primary palm hyperhidrosis, discusses comfort options, and sets a transparent plan and cost in English.
After numbing, the grid of 15 to 25 injections per hand is completed in roughly 20 to 30 minutes total.
Downtime is minimal, so most patients use their hands normally soon after, avoiding heavy grip for the rest of the day.
Sweating drops noticeably within about 1 week, giving dry, comfortable palms for daily tasks and social situations.
The effect lasts around 6 months, then fades, so repeat sessions maintain dryness as part of ongoing management.
Palm hyperhidrosis is excessive sweating of the hands caused by overactive nerve signals to the sweat glands. It is treated with botulinum toxin type A, injected across the palm to block those signals. Relief typically lasts around 6 months. You can learn more on our botox injection page.
Botulinum toxin type A blocks acetylcholine, the messenger that tells sweat glands to activate. Injected as a grid across the palm, it interrupts that signal and sharply cuts sweat production in the treated area. Unlike antiperspirants that sit on the surface, it works at the nerve-to-gland level, which is why relief is stronger and longer.
Each palm typically receives a grid of about 15 to 25 shallow intradermal injections so the toxin covers the sweat-gland field evenly. The exact number depends on your hand size and the area affected. A doctor maps the grid at your appointment to ensure even, thorough coverage for consistent dryness.
The palm is sensitive, so injections can be uncomfortable, but comfort measures make it manageable. Doctors use topical numbing, cooling, or a nerve block before starting. Most patients describe brief stinging rather than lasting pain, and the session is short. Discussing comfort options at consultation helps set expectations before treatment.
Sweat production usually drops noticeably within about 1 week of treatment, with full effect over the following days. You will feel your palms staying dry through daily tasks like writing and gripping. If any area still sweats, a doctor can review coverage and add a small top-up if appropriate.
Relief from palm hyperhidrosis typically lasts around 6 months per session before sweating gradually returns as the toxin wears off. It is a managed condition, not a one-time fix, so repeat sessions maintain dryness. Many patients plan two treatments a year. Related injection treatments can be coordinated in the same plan.
For most people, hand strength and sensation are preserved because the toxin targets sweat glands, not the working muscles. Occasionally a small, temporary reduction in grip is reported, which resolves on its own. A doctor injects shallowly and precisely to minimise this, so everyday hand function stays largely unaffected.
Botulinum toxin type A is well studied for focal hyperhidrosis and generally well tolerated when a doctor injects appropriate doses. Side effects are usually mild and temporary, such as minor tenderness. A botox consultation screens for contraindications like pregnancy or neuromuscular conditions to keep treatment appropriate for you.
Palm hyperhidrosis produces far more sweat than the body needs to cool itself, often dripping or soaking the hands even at rest. It is usually primary, meaning no underlying illness, and about 90% of focal cases are like this. A doctor confirms the diagnosis and rules out secondary causes before treatment.
Yes, antiperspirants can complement botox, especially near the end of a session’s effect or for mild residual sweating. Botox handles the heavier sweating at the nerve level, while surface products help with maintenance. A doctor can advise how to combine them so your palms stay comfortably dry between injection sessions.
Yes, botulinum toxin type A also treats underarm and, in some cases, sole or facial sweating using the same signal-blocking mechanism. If you sweat excessively in more than one area, a doctor can plan treatment across sites. This is discussed as part of a tailored botox plan at consultation.
Adults with moderate to severe primary palm sweating that antiperspirants have not controlled are typically good candidates. A consultation confirms the diagnosis and screens for contraindications like pregnancy or neuromuscular disorders. This can be planned alongside other injection treatments if you have concerns in several areas.
Our Gangnam (Seoul) location with Dr. Yoongon Ryu treats palm hyperhidrosis, about 2 minutes from Gangnam Station exit 10, with full English support. We also have Myeongdong and Incheon Airport locations, so international patients can choose whichever best fits their schedule while in Seoul.
Avoid heavy gripping, intense hand exercise, and soaking your hands for the rest of the treatment day. Keep the palms clean and dry, and skip strong heat sources briefly. Gentle skin care for the hands helps. Most patients return to normal hand use quickly, and written aftercare is provided.
The treatment needs only one short visit, so a 1 to 2 day stay is enough. Because full dryness develops over about a week, many international patients see results after returning home. Our English-speaking team can arrange a remote check-in so you can confirm your response without a second trip.
Yes, flying soon after treatment is generally fine, as it is minimally invasive with little downtime. Just avoid heavy gripping and hand strain during travel that day. If you notice any uneven dryness once results settle, our team can advise remotely and plan any adjustment on a future visit.
| Botox (Botulinum Toxin Type A) | Prescription Antiperspirants | Energy-Based Sweat Devices | |
|---|---|---|---|
| Mechanism | Blocks nerve signals to sweat glands | Blocks sweat ducts at the skin surface | Uses energy to reduce gland activity |
| Best for | Moderate to severe palm sweating | Mild sweating or maintenance | Mainly underarm, less common for palms |
| Onset | Within about 1 week | Days, but often incomplete on palms | Gradual over sessions |
| Downtime | Minimal | None | Varies by device |
| Duration of effect | Around 6 months per session | Needs frequent reapplication | Varies, often longer-term goal |
| Suited to palms | Well suited, targeted grid | Less effective on thick palm skin | Limited for palm use |
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