Gangnam
Dr. Yoongon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices
Intradermal botox quietens overactive sweat glands so palms usually feel drier within 3 to 7 days, with the effect lasting about 4 to 6 months per session.
Palm hyperhidrosis treatment in Seoul uses intradermal botox (botulinum toxin type A) injected across both palms to temporarily block the nerve signals driving excessive sweating, so the hands feel dry. Palms usually turn drier within 3 to 7 days, and the effect lasts about 4 to 6 months, so patients repeat it roughly twice a year.
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Palm hyperhidrosis is excessive, uncontrollable sweating of the palms beyond what the body needs for temperature control. It can soak paper, loosen grip, and affect confidence in handshakes, keyboards, or holding a phone. When topical antiperspirants are not enough, intradermal botox is a widely used, non-surgical option that temporarily switches off the overactive sweat glands in the treated area.
The treatment uses botox (botulinum toxin type A), the same neuromodulator used for expression lines, but here it is placed shallowly into the skin of the palm rather than into muscle. Across a mapped grid of small injections, the toxin blocks the chemical signal that tells sweat glands to activate, so the palm produces far less sweat for several months. It does not cure the tendency to sweat; it manages it on a repeated schedule.
This approach suits international patients visiting Seoul, Korea, because the appointment is short and downtime is minimal. At Reberry Clinic, the clinic’s doctors first confirm the sweating is primary hyperhidrosis, then map both palms and dose conservatively for comfort. Our English-speaking team supports you at our operating Seoul locations (Gangnam, Myeongdong) and near Incheon Airport.
Sweating is triggered when nerves release acetylcholine onto the eccrine sweat glands in the skin. Botulinum toxin type A temporarily blocks that release, so the treated glands stop being stimulated and sweat output falls sharply. For palms, the toxin is delivered intradermally, meaning shallow, evenly spaced deposits across the palm surface rather than deep muscle injections, so it targets the sweat glands while sparing hand strength as much as possible. Because the palm is large and densely populated with glands, the doctor maps a grid of injection points roughly 1 to 2 cm apart, and both hands are usually treated in one visit since the condition is typically symmetrical. The effect is not permanent: nerve endings gradually regenerate their connections over about 4 to 6 months, so sweating slowly returns and the treatment is repeated. This is a targeted, reversible way to control the symptom rather than a surgical procedure, which is why it is popular with people who want relief without the risks of surgery.
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The doctor confirms primary palm hyperhidrosis across both palms, sometimes using a starch-iodine test to highlight the 2 most active sweating zones.
Because palms are sensitive, topical numbing, cooling, or a nerve block is applied for about 20 to 30 minutes before injections.
Both palms are marked on a grid with points roughly 1 to 2 cm apart so the toxin covers the whole sweating area.
Small units of botulinum toxin type A are placed shallowly at each point across both hands in a single session.
Palms usually feel drier within 3 to 7 days, with the full effect by about 2 weeks as the glands are quietened.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
The clinic’s doctors confirm primary hyperhidrosis, grade your sweating, and explain the plan and expectations in English.
After about 20 to 30 minutes of numbing, both palms are injected in a single session and you can leave the same day.
One session treats both hands, and the effect is temporary, so repeat visits are planned every 4 to 6 months.
Palms usually feel drier within 3 to 7 days and reach full effect by about 2 weeks.
Dryness lasts about 4 to 6 months; avoid heavy hand use and hot water for a few hours, then repeat to maintain relief.
Palm hyperhidrosis treatment uses intradermal botox (botulinum toxin type A) injected across both palms to temporarily block the nerve signals driving excessive sweat. It manages sweaty palms for several months rather than curing them. You can read the modality basics on our botox injection page before your visit.
Botulinum toxin type A blocks acetylcholine, the chemical that signals sweat glands to activate, so treated glands stop producing sweat. Because it is placed shallowly in the skin across a mapped grid, it targets sweating while sparing hand strength. The effect covers the injected area and lasts until nerve signals gradually recover months later.
Most people notice drier palms within 3 to 7 days, with the full effect by about 2 weeks as the glands are quietened. This gradual onset is normal for botulinum toxin type A. Your doctor reviews the response so future sessions can be fine-tuned to your sweating pattern and comfort.
Dryness typically lasts about 4 to 6 months per session before sweating gradually returns as nerve signals recover. Duration varies with dose, hand size, and metabolism. Most patients repeat treatment roughly twice a year to stay comfortable, and consistency often makes the relief feel more predictable over time.
Palms are sensitive, so injections can sting more than facial areas, which is why numbing cream, cooling, or a nerve block is applied first. Most patients find the treatment very manageable with these measures. The whole process is quick, and any discomfort is brief and settles right after the session.
Downtime is minimal, and most people return to normal activity the same day. You may feel brief tenderness or slight temporary grip weakness that settles within days. Avoid heavy gripping and hot water for a few hours. This low-downtime profile makes the treatment convenient for international patients on a short trip.
One session treats both palms, and because the effect is temporary, maintenance is planned every 4 to 6 months. There is no need for a fixed course; you simply repeat when sweating returns. Your doctor helps you set a realistic rhythm and can adjust the dose at each visit based on your response.
Mild, temporary grip weakness can occasionally occur because some hand muscles sit near the sweat glands, but it is usually minor and short-lived. Intradermal, conservative dosing minimises this. Your doctor places injections shallowly and carefully to protect strength. Report any bothersome weakness so future dosing can be adjusted for you.
Most side effects are mild and temporary, such as minor tenderness, small bruises, or brief grip weakness at injection sites. Serious effects are uncommon with proper technique. Choosing a trained doctor and conservative intradermal dosing reduces risks. Your doctor reviews your health history first and explains what to watch for after treatment.
Botox reduces palm sweating for months from a single session, while prescription antiperspirants must be used regularly and mainly suit milder cases. Many people use antiperspirants for maintenance and botox for stronger, longer relief. Your doctor can combine approaches, and related options are outlined on our injection treatment page.
Good candidates are adults with primary palm hyperhidrosis that antiperspirants cannot control, and no contraindications such as pregnancy or neuromuscular disease. If sweating stems from an underlying condition, that is reviewed first. A consultation confirms the diagnosis and whether intradermal botox is the right option for your hands.
Avoid heavy hand use, hot water, saunas, and rubbing the palms for a few hours after treatment so the toxin settles. Keep hands clean and dry. These simple steps help results develop evenly. Your doctor gives tailored aftercare, and gentle skin care keeps the palm skin comfortable between sessions.
Intradermal botulinum toxin type A is widely used for sweaty palms and generally considered safe when dosed by a trained doctor. Temporary tenderness or mild grip weakness can occur and resolves as the toxin balances. Contraindications include pregnancy and neuromuscular disorders. You can review the modality overview on our botox injection page.
Yes, some patients treat palms alongside underarms or soles in the same visit, since hyperhidrosis often affects several areas. Each zone is mapped and dosed separately for safety. Related options are outlined on our injection treatment page, and your doctor explains how treating them together affects the plan.
One day is often enough for the treatment itself, but 2 to 3 days is comfortable if you want a short review or other appointments. Because dryness builds over 1 to 2 weeks, many international patients treat early in their stay. Our English-speaking team helps schedule the visit around your travel plans.
Yes, flying within a day is generally fine, as palm injections are minimally invasive with little downtime. International patients can complete treatment in one visit and arrange remote check-ins in English, planning repeat rounds around future trips. You can keep using supportive skin care at home, and your dosing notes stay on file.
| Intradermal Botox | Prescription Antiperspirants | Energy/Microwave Options | |
|---|---|---|---|
| Mechanism | Botulinum toxin type A blocks sweat-gland nerve signals | Aluminium salts plug sweat ducts topically | Heat energy targets sweat glands |
| Best for | Moderate to severe palm sweating | Mild sweating or maintenance | Selected areas, device-dependent |
| Pain / comfort | Numbing used, brief stinging | Painless, can irritate skin | Numbing used, warmth or pressure |
| Downtime | Minimal | None | Varies by device |
| Results timeline | Drier in 3 to 7 days | Daily use, gradual | Builds over weeks |
| Longevity | About 4 to 6 months | Only while used regularly | Longer-lasting for some areas |
| Cost drivers | Units and both-hand treatment | Ongoing product cost | Device and sessions |
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