Gangnam
Dr. Yoon-Gon Ryu
Aesthetic Medicine Specialist
Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)
Rejuran HB pairs 2 active components, salmon-derived polynucleotides (PN) and hyaluronic acid (HA), so 1 booster addresses both skin repair and deep hydration in the same session.
Rejuran HB is a hybrid injectable skin booster that combines salmon-derived polynucleotides (PN) with hyaluronic acid, delivered into the dermis to hydrate, smooth fine lines, and improve skin firmness and glow. At our Gangnam (Seoul) location, Dr. Yoongon Ryu tailors the plan, typically a short series spaced weeks apart, to your skin.
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Rejuran HB is a hybrid skin booster that blends two well-studied ingredients into one injectable: salmon-derived polynucleotides (PN) and hyaluronic acid (HA). The PN component supports the skin’s own repair and collagen-supporting environment, while the HA gives an immediate hydration and plumping effect. Because the two work on different timelines, patients often notice early moisture and glow while the longer-term skin-quality benefits build over the weeks that follow.
Within the Rejuran family, the original Rejuran (Healer) is a PN-focused booster for overall skin quality, Rejuran I is formulated for the delicate under-eye area, and Rejuran HB adds hyaluronic acid for people who also want a hydration and plumping boost. HB is often chosen for dry, dull, or early-aging skin where both repair and moisture are the goals.
At Reberry Clinic, Rejuran HB is delivered as a consultation-led treatment. At our Gangnam (Seoul) location, Dr. Yoongon Ryu assesses your skin, explains whether HB or another booster suits you, and maps out a short series. International patients receive full English support, and the clinic sits about 2 minutes from Gangnam Station exit 10, making it easy to reach.
Rejuran HB is built on polynucleotides (PN), long chains of nucleotides purified from salmon DNA that are biocompatible with human skin. When injected into the dermis, PN acts as a supportive scaffold and helps create an environment that encourages the skin’s own fibroblasts and repair activity, which over time can improve elasticity, texture, and fine lines. This is a regenerative, skin-quality approach rather than a volumizing filler. The added hyaluronic acid is a powerful humectant that binds water, so it delivers fast, visible hydration and a smoother, plumper surface almost immediately. Combining the two means one product addresses both the slower repair pathway of PN and the instant moisture pathway of HA. Rejuran HB is not a heat- or ultrasound-based device treatment and does not use radiofrequency or laser energy; its effect comes purely from what is injected and how the skin responds to it.
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Your doctor grades hydration, texture, and fine lines to decide if Rejuran HB, with its 2-part PN plus HA formula, fits your goals.
A topical anaesthetic is applied for about 20 to 30 minutes so the micro-injections are comfortable across the treatment area.
Rejuran HB is placed with fine needle micro-injections across the face, a session that usually takes about 20 to 30 minutes.
The hyaluronic acid binds water almost immediately, so many patients notice added moisture and plumpness within the first few days.
The polynucleotide component supports skin repair gradually, with texture and elasticity typically building over roughly 4 to 8 weeks.
Most plans use 2 to 4 sessions spaced about 2 to 4 weeks apart, then occasional maintenance to sustain results.
Reberry Clinic · Prices verified: Oct 2026
| Clinic | Price (KRW) |
|---|---|
| All Reberry Clinic locationsRejuran HB 1cc | from₩230,000 |
VAT excluded · Final price depends on treatment scope and skin condition · Confirmed after consultation
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
At our Gangnam (Seoul) location, Dr. Yoongon Ryu assesses your skin in English and confirms whether Rejuran HB suits your hydration and skin-quality goals.
After numbing cream, the micro-injection session usually takes about 20 to 30 minutes, with small bumps that settle within a day or two.
Rejuran HB is planned as a short series, so your doctor maps out the number of sessions and spacing at consultation.
Hydration often shows within days, while texture, elasticity, and glow continue to build over roughly 4 to 8 weeks.
Results are refreshed with occasional maintenance every few months; gentle skincare and daily sunscreen help protect the improvement.
Rejuran HB combines salmon-derived polynucleotides (PN) with hyaluronic acid, whereas the original Rejuran (Healer) is PN-focused. The added HA gives Rejuran HB an immediate hydration and plumping effect on top of PN skin repair. You can read more on our Rejuran Healer page.
No, Rejuran HB is a skin booster, not a volumizing filler. It works by improving skin quality, hydration, and firmness across the dermis rather than adding shape or contour. If you want structural volume, a separate dermal filler is more appropriate, which your doctor can explain during your consultation in Gangnam.
Rejuran HB targets dryness, dullness, rough texture, fine lines, and mild loss of firmness. The PN component supports repair and elasticity over several weeks, while the HA delivers fast hydration. It suits people who want both skin repair and a moisture boost from a single booster rather than one effect alone.
Discomfort is mild because a topical anaesthetic is applied for about 20 to 30 minutes beforehand. You may feel small pin-pricks from the micro-injections and brief stinging, but most patients tolerate it well. A trained doctor adjusts technique and depth to keep the session comfortable across the treated area.
Downtime is minimal, typically brief redness and small raised bumps at injection points that usually settle within 1 to 2 days. Some patients see minor bruising that fades over a few days. Because recovery is short, Rejuran HB fits busy schedules and is popular with international patients on a tight itinerary.
Hydration and a plumper feel often appear within the first few days thanks to the hyaluronic acid. The polynucleotide repair effect builds more gradually, with texture, elasticity, and glow typically improving over 4 to 8 weeks and continuing across a series. Your doctor tracks progress between sessions.
Most plans use 2 to 4 sessions spaced about 2 to 4 weeks apart, then occasional maintenance. The exact number depends on your skin’s baseline condition and goals. Your doctor confirms the schedule at consultation and adjusts it based on how your skin responds between visits.
Results commonly last several months and are refreshed with periodic maintenance, so Rejuran HB is managed over time rather than being a one-time fix. Longevity depends on age, skin condition, and lifestyle. A gentle skin care routine and daily sun protection help sustain the improvement.
Yes, Rejuran HB is often combined with energy-based lifting or resurfacing for a fuller result, sequenced safely by your doctor. For example, some patients pair it with Ultherapy Prime for firmness. The clinic staggers treatments so the skin is not over-stressed in a single visit.
Rejuran HB is a PN plus HA repair-and-hydration booster, while Juvelook is a PDLLA collagen stimulator that firms gradually over months. HB suits dry, dull skin wanting quick moisture plus repair; Juvelook suits those prioritising long-term firmness. Many patients discuss both and choose based on their main goal.
Common effects are temporary redness, small bumps, mild swelling, and occasional bruising at injection sites, all of which usually resolve within days. Serious reactions are uncommon when performed by a trained doctor. A consultation reviews allergies and medical history to reduce risk, and your doctor explains what to expect beforehand.
Rejuran HB is not suitable during pregnancy or breastfeeding, with an active skin infection, or with a known allergy to salmon-derived products. People on blood thinners or with a keloid-scarring history need careful assessment first. Your doctor reviews your history at consultation to confirm whether the booster is safe for you.
Rejuran HB is generally suitable across skin tones because it is injected rather than heat- or light-based, so it does not carry the pigment risk of some lasers. A consultation confirms your skin is healthy and appropriate. You can explore related options on our injectable treatments page.
Keep the area clean, avoid heavy makeup, saunas, and intense exercise for about a day, and use gentle skincare with daily sunscreen. Avoid alcohol immediately after to limit bruising. A supportive skin care routine protects your investment between sessions and helps your skin recover smoothly.
Rejuran HB is available at our Gangnam (Seoul) location, where Dr. Yoongon Ryu tailors your plan. The clinic sits about 2 minutes from Gangnam Station exit 10 in Seoul, Korea, with English-speaking support. Reberry Clinic also operates Myeongdong and Incheon Airport locations, so care can be arranged around your travel.
For a single session, 1 to 2 days in Seoul is comfortable, covering a consultation, the treatment, and any small bumps settling. Because Rejuran HB works best as a short series, many international patients begin in Gangnam and continue on return visits. Our English team helps coordinate the timing around your trip.
Yes, flying within a day of Rejuran HB is generally fine because it is minimally invasive with short downtime. Cabin air is drying, so moisturise well and protect treated skin from sun. If you had extensive injections, your doctor will give tailored aftercare advice to follow while you travel home.
International patients can start a Rejuran HB series in Seoul and continue on return trips, and the clinic offers English remote check-ins between visits to keep the plan on track. Your treatment notes are kept on file for continuity, and you can maintain results with home skincare between appointments.
| Rejuran HB | Rejuran (Healer) | Juvelook | |
|---|---|---|---|
| Main ingredient | Salmon polynucleotides (PN) plus hyaluronic acid | Salmon polynucleotides (PN) | PDLLA collagen stimulator |
| Best for | Dry, dull skin wanting repair plus hydration | Overall skin quality and fine lines | Building firmness and collagen over months |
| Immediate effect | Hydration and plumping from the HA | Subtle, mostly builds gradually | Little immediate change, works over time |
| Pain / comfort | Micro-injections under numbing cream | Micro-injections under numbing cream | Injections under numbing cream |
| Downtime | Minimal, brief redness or small bumps | Minimal, brief redness or small bumps | Minimal, occasional swelling |
| Results timeline | Early hydration, quality builds over weeks | Builds over several weeks | Gradual over 2 to 3 months |
| Sessions | Usually 2 to 4 in a series | Usually 3 to 4 in a series | Often 1 to 2, spaced out |
| Cost factors | Depends on area and number of sessions | Depends on number of sessions | Depends on vials and sessions |
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