Gangnam
Dr. Yoon-Gon Ryu
Aesthetic Medicine Specialist
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Rejuran Healer delivers purified polynucleotide (PN) from salmon DNA into the mid-dermis over a typical course of 3 sessions spaced 2 to 4 weeks apart to rebuild skin quality from within.
Rejuran Healer is a polynucleotide (PN) skin booster that injects purified salmon-derived DNA fragments into the mid-dermis to improve skin texture, elasticity, and hydration. At our Gangnam (Seoul) location, Dr. Yoongon Ryu typically plans a course of 3 sessions, 2 to 4 weeks apart, with results building gradually over the following weeks.
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Rejuran Healer is an injectable skin booster based on polynucleotide (PN), a purified fragment of salmon-derived DNA. Rather than filling or freezing tissue, it works as a regenerative signal: micro-injections into the mid-dermis prompt fibroblasts to build collagen and improve the skin’s own structure. The goal is better skin quality, meaning smoother texture, improved elasticity, and a healthier, more hydrated look, rather than added volume.
It is often chosen by people whose skin feels dull, crepey, or dehydrated, or who have fine lines and enlarged pores that a topical routine alone cannot resolve. Because it treats the skin as a whole rather than a single wrinkle, it suits patients wanting an overall glow and resilience upgrade instead of a targeted correction. Rejuran Healer is the classic face variant in the Rejuran family, which also includes eye and hybrid formulations for different zones.
At Reberry Clinic, Rejuran Healer is consultation-led. At our Gangnam (Seoul) location, Dr. Yoongon Ryu assesses your skin, explains what a realistic course looks like, and tailors the number of sessions to your skin condition. International patients are supported in English, and Gangnam is easily reached about 2 minutes from Gangnam Station exit 10.
Polynucleotide is a chain of purified DNA fragments, in Rejuran’s case sourced from salmon and refined to remove proteins that could trigger a reaction. Once injected into the mid-dermis, PN acts on fibroblasts and supporting pathways to encourage type I collagen synthesis, improve microcirculation, and support the skin’s water-holding capacity. It is not a filler and does not add hyaluronic-acid volume; instead it nudges the skin to repair and remodel itself over roughly 4 to 8 weeks. This is why Rejuran Healer is described as a regenerative or reparative booster rather than a contouring treatment. Because the effect is biological and gradual, a series of 2 to 4 sessions is standard, and maintenance every 6 to 12 months helps sustain results. The delicate, even placement of many small injections is what makes doctor technique and depth control important, which is why the treatment is planned and performed under medical assessment rather than as a fixed one-size protocol.
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Dr. Yoongon Ryu grades your texture, elasticity, and hydration to decide whether Rejuran Healer or a different booster fits, and how many of the usual 3 sessions you may need.
A topical anaesthetic is applied for about 20 to 30 minutes so the many small injections stay comfortable.
Purified polynucleotide is placed into the mid-dermis across the treatment area in a grid of small injections, usually taking 15 to 20 minutes.
Over the next 4 to 8 weeks, fibroblasts respond by producing collagen and improving skin quality, so results build gradually rather than instantly.
Most plans run 2 to 4 sessions spaced 2 to 4 weeks apart, with maintenance every 6 to 12 months to sustain the improvement.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.
At our Gangnam (Seoul) location, Dr. Yoongon Ryu assesses your skin quality in English and explains whether Rejuran Healer suits your goals and how many sessions to plan.
After about 20 to 30 minutes of numbing, the injection session itself takes roughly 15 to 20 minutes.
A full course is usually 2 to 4 sessions spaced 2 to 4 weeks apart, so plan across several visits rather than one appointment.
Small bumps settle within a day or two, and skin quality improves gradually over the following 4 to 8 weeks as collagen builds.
Results can last several months; maintenance every 6 to 12 months plus daily sunscreen and hydration help sustain the improvement.
Rejuran Healer is a polynucleotide (PN) skin booster made from purified salmon DNA that is injected into the mid-dermis to improve texture, elasticity, and hydration. It works by prompting your own fibroblasts to build collagen, so it renews skin quality rather than adding volume. Learn more on our Rejuran Healer page.
Rejuran Healer is performed at our Gangnam (Seoul) location, on Gangnam-daero, about 2 minutes from Gangnam Station exit 10. Dr. Yoongon Ryu plans and performs the treatment with English-language support for international patients. A consultation confirms whether it suits your skin before any session is booked.
No, Rejuran Healer is not a filler. Fillers use hyaluronic acid to add structural volume, while Rejuran uses polynucleotide to regenerate skin quality, meaning texture, elasticity, and hydration. You can compare related options such as injectable fillers to see how the two differ in purpose and result.
Most people have a course of 2 to 4 sessions spaced about 2 to 4 weeks apart, with 3 being a common plan. The exact number depends on your starting skin quality and goals. After the initial course, maintenance every 6 to 12 months helps sustain results, which your doctor confirms at consultation.
Discomfort is usually mild because a topical anaesthetic is applied for about 20 to 30 minutes before the many small injections. Most patients describe brief stinging or pressure rather than sharp pain. Tiny bumps and slight redness are normal afterwards and typically settle within a day or two.
Downtime is minimal for most people. Small injection bumps and mild redness usually resolve within 24 to 48 hours, and light bruising, if any, fades over a few days. Many patients return to normal activities the same day, which makes it convenient for international visitors on a short trip.
Visible improvement builds gradually over 4 to 8 weeks as collagen production increases, rather than appearing immediately after one session. Skin often looks more hydrated first, with texture and elasticity improving across the course. Your doctor reviews progress between sessions to keep the plan matched to your response.
Results can last several months after a completed course, though this varies with age, skin condition, and lifestyle. Because it is a regenerative booster and not a one-time fix, maintenance sessions every 6 to 12 months help sustain smoother, more elastic skin. Daily sun protection also extends how long results hold.
Yes, Rejuran Healer is often combined with treatments like lasers or energy-based lifting, sequenced safely across appointments. For example, it pairs well with a skin care routine or, in some plans, energy devices. Your doctor sequences procedures so the skin is not over-stressed and each treatment supports the others.
Rejuran Healer is widely used and generally well tolerated when performed by a trained doctor, since the polynucleotide is purified to reduce reaction risk. Common effects are minor and short-lived, such as swelling, redness, small bumps, or bruising. A consultation screens for allergies and contraindications to keep the treatment appropriate for you.
The most common side effects are mild and temporary: injection-site redness, small bumps, swelling, tenderness, or occasional bruising that fades within days. Serious reactions are uncommon. Anyone with a salmon allergy or active skin infection should tell the doctor, as these need review before Rejuran Healer is considered.
Good candidates are adults with dull, crepey, or dehydrated skin, fine lines, or enlarged-looking pores who want overall renewal rather than added volume. It suits many skin types. A consultation confirms suitability and rules out contraindications like pregnancy, salmon allergy, or active skin infection before starting a course.
Rejuran Healer uses polynucleotide to regenerate skin structure, while a hyaluronic-acid water-glow booster mainly hydrates and plumps for a quicker, shorter-lived glow. Many patients use them for different goals or in sequence. Your doctor recommends which fits your skin, or whether a glass-skin approach combining treatments suits you better.
Rejuran Healer can improve skin texture and the look of enlarged pores as it boosts collagen and repair, though deep or pitted acne scars usually need dedicated resurfacing. It is often used as part of a broader plan for skin renewal. Your doctor assesses your scarring and advises whether it should be combined with other options.
For a single session, 1 to 2 days in Seoul is comfortable, allowing a consultation, the treatment, and brief recovery from minor bumps. Because a full course runs over several weeks, many international patients start in Gangnam and continue on return visits. Our English-speaking team helps coordinate timing around your travel.
Yes, flying within a day or so is generally fine, as Rejuran Healer is minimally invasive with little downtime. Small bumps and redness usually settle quickly. Cabin air is drying, so moisturise and protect treated skin from sun, and avoid heavy makeup over injection sites for the first day as your doctor advises.
International patients can complete a course across one or more trips, and the clinic offers remote check-ins in English between visits so your plan stays on track. You can maintain results at home with sunscreen and a supportive skin care routine. Your treatment notes are kept on file for continuity.
| Rejuran Healer | HA Skin Booster | HA Dermal Filler | |
|---|---|---|---|
| Mechanism | Polynucleotide (PN) regenerates skin quality | Hyaluronic acid hydrates and plumps the skin | Hyaluronic acid adds structural volume |
| Main goal | Texture, elasticity, and overall skin repair | Immediate hydration and glow | Shape, contour, and volume correction |
| Best for | Dull, crepey, dehydrated skin wanting renewal | Skin needing a quick hydration lift | Cheeks, lips, or contours needing volume |
| Results timeline | Builds over weeks across a series | Fairly quick, shorter-lived | Immediate, then settles |
| Sessions | A course of 2 to 4, then maintenance | Often repeated for upkeep | Usually one session per area |
| Downtime | Minimal, brief bumps or redness | Minimal | Minimal to mild swelling or bruising |
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