
Dr. Yoon-Gon Ryu
Flagship clinic · KOL for leading lifting & regenerative devices · Featured in Authority Magazine (2026)
Two injectable tools cover most facial wrinkles: botulinum toxin relaxes the muscles behind dynamic lines, while HA filler refills static folds that linger at rest, often paired in 1 tailored session.
Wrinkle treatment in Gangnam, Seoul, Korea combines two injectables: botulinum toxin relaxes overactive muscles behind dynamic lines like frown and forehead creases, while hyaluronic acid filler refills static folds that stay visible at rest. At our Gangnam (Seoul) location, Dr. Yoongon Ryu maps which lines need which tool at consultation.
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Wrinkle treatment is a non-surgical, injectable approach to softening facial lines, and the right tool depends on how a wrinkle behaves. Dynamic wrinkles appear when you move, such as frown lines between the brows, horizontal forehead lines, and crow’s feet, and they respond to botulinum toxin, which gently relaxes the muscle that folds the skin. Static wrinkles stay etched even when your face is still, such as deep nasolabial folds, and these are better refilled with hyaluronic acid (HA) dermal filler.
Because most faces show a mix of both, wrinkle treatment in Seoul is usually a combined, individualised plan rather than a single product. A doctor assesses which lines are muscle-driven and which are volume-driven, then chooses botulinum toxin, HA filler, or both. Results are temporary and build a natural, refreshed look rather than a frozen one, so many patients return for maintenance.
At Reberry Clinic, wrinkle care is consultation-led and delivered with full English support. International patients are seen at our Gangnam (Seoul) location, roughly 2 minutes from Gangnam Station exit 10, where Dr. Yoongon Ryu grades each line and explains the plan and its cost transparently before anything is injected.
Botulinum toxin type A is a neuromodulator: injected in tiny units into a target muscle, it blocks the nerve signal that tells the muscle to contract, so the overlying skin stops creasing. Its effect on facial lines typically lasts about 3 to 4 months as nerve terminals gradually regrow, which is why it is repeated. It is ideal for dynamic upper-face lines such as the glabella (frown), forehead, and crow’s feet. Hyaluronic acid filler works differently: HA is a sugar molecule that binds water, so a cross-linked HA gel placed under a static fold physically restores volume and support, smoothing the line from beneath. Depending on the HA product and area, filler results can last roughly 12 to 24 months. Because the two tools target different causes, a doctor often combines them, relaxing the muscle that keeps re-folding the skin while refilling the crease that has already set, so neither is over-used. Dosing, injection depth, and product choice are individualised, which is why an in-person assessment matters more than any fixed menu.
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The doctor sorts your wrinkles into 2 groups: dynamic lines that appear on movement and static folds visible at rest, which decides the tool.
Botulinum toxin is placed in small units into muscles like the glabellar complex and forehead; onset is usually seen within 3 to 7 days.
Cross-linked HA filler is layered under set creases such as nasolabial folds to restore volume, using 1 or more syringes depending on depth.
The doctor treats areas in proportion so 2 sides stay symmetrical and expression is preserved rather than blocked.
Toxin is typically repeated around every 3 to 4 months and HA filler every 12 to 24 months, adjusted to how your lines respond.
See representative outcomes from Reberry Clinic. Results build gradually and vary by individual; your plan is assessed at consultation.





At our Gangnam (Seoul) location, Dr. Yoongon Ryu grades each line, explains whether toxin, HA filler, or both fit, and outlines cost in English.
A combined session usually takes about 20 to 40 minutes, with numbing applied before filler and quick injections for toxin areas.
Toxin softening appears within 3 to 7 days and peaks around 2 weeks; HA filler shows volume immediately, then settles over a few days.
Dynamic lines ease first as the muscle relaxes, while static folds look refilled right away and refine as swelling subsides.
Toxin is repeated about every 3 to 4 months and HA filler every 12 to 24 months; avoid heat and heavy exercise for 24 hours after.



The right wrinkle treatment depends on how your lines behave: dynamic lines that appear on movement suit botulinum toxin, while static folds visible at rest suit HA filler. Many faces need both, so a doctor assesses each line before choosing. You can start on our botox injection page.
Botulinum toxin relaxes the muscle that folds the skin, softening dynamic lines like frown and forehead creases within days. HA filler instead adds volume under a set fold to smooth it physically. One addresses movement, the other addresses lost volume, which is why they are often combined in one plan.
Botulinum toxin works best on upper-face dynamic lines: the glabellar frown between the brows, horizontal forehead lines, and crow’s feet at the eyes. These appear when muscles contract, so relaxing the muscle stops the skin creasing. It is less suited to deep folds that are visible even when your face is completely still.
HA filler suits static wrinkles that stay etched at rest, most commonly the nasolabial folds running from nose to mouth. Because these are volume-driven, a cross-linked HA gel refills and supports the crease from beneath. You can explore related options on our injectable fillers page.
Discomfort is usually mild and brief. Toxin injections feel like quick pinches and need no numbing for most people. For HA filler, a topical numbing cream is applied and the product itself contains lidocaine, so the area stays comfortable. Any tenderness typically settles quickly after your session.
Downtime is generally minimal. Toxin areas may show tiny temporary bumps that fade within an hour, and most people return to normal activity immediately. Filler can cause short-lived bruising or swelling for a few days. Avoiding heat, alcohol, and heavy exercise for 24 hours helps recovery.
HA filler shows volume immediately, refining over a few days as swelling settles. Botulinum toxin is more gradual: softening begins within 3 to 7 days and reaches its full effect around 2 weeks. In a combined plan, folds look filled first while dynamic lines ease over the following days.
Results are temporary and vary by tool. Botulinum toxin softening typically lasts about 3 to 4 months before movement gradually returns. HA filler lasts longer, roughly 12 to 24 months depending on the product and area. Because effects fade, wrinkle treatment is maintained over repeat visits rather than done once.
A carefully dosed plan aims to soften lines while preserving natural expression, not to freeze the face. The doctor treats muscles in proportion and keeps both sides balanced. Conservative dosing and a focus on refreshed movement help avoid an over-treated look, which is why an experienced injector matters.
Yes, combining them in a single session is common because they treat different causes: toxin relaxes the muscle while filler refills the set fold. This layered approach often gives a more balanced result than either alone. Your doctor sequences the areas so dosing stays conservative and the face stays symmetrical.
HA filler has an advantage here: because it is hyaluronic acid, an enzyme called hyaluronidase can dissolve it if you are unhappy or if adjustment is needed. Botulinum toxin is not reversed but simply wears off over months. This flexibility is one reason HA is a popular choice for folds.
Most healthy adults with dynamic lines, static folds, or both are suitable candidates. A consultation confirms which tool fits and rules out contraindications like pregnancy or certain neuromuscular conditions. Your doctor also checks the treatment area is free of active infection before recommending toxin, filler, or a combined plan.
Botulinum toxin and HA fillers are widely used and generally well tolerated when placed by a trained doctor at appropriate doses. Common effects are temporary redness, minor bruising, or swelling. A consultation reviews your history to lower risks. You can read more on our botox injection page.
Cost depends on which tools you need, how many areas are treated, and the amount of product used, so it is confirmed at consultation rather than fixed. A toxin-only plan differs from a combined plan using injectable fillers. At our Gangnam location, the cost is explained transparently in English before you decide.
Wrinkle treatment is provided at our Gangnam (Seoul) location, in the Gangnam-daero area about 2 minutes from Gangnam Station exit 10, with Dr. Yoongon Ryu. It is easy to reach for international patients, and our English-speaking team helps coordinate timing. You can also review our injectable fillers page.
Stay upright for a few hours, avoid rubbing treated areas, and skip heavy exercise, alcohol, saunas, and sun for about 24 hours. For toxin, do not massage the injected muscles that day. These simple steps help the product settle evenly and reduce the chance of bruising or spreading.
For most patients, 1 to 2 days is enough: a consultation and the injections can often happen the same day, with a short check if filler is used. Because toxin takes about 2 weeks to peak, many international patients fly home before the full effect appears, which is completely normal.
Yes, flying within a day or so is generally fine after injectable wrinkle treatment, which is non-surgical. To reduce swelling or bruising while you travel, stay hydrated and avoid alcohol. If you had filler, your doctor will advise on gentle aftercare, and you can continue a supportive skin care routine at home.
| Botulinum Toxin | HA Dermal Filler | Combined Plan | |
|---|---|---|---|
| Mechanism | Relaxes the muscle that folds the skin | Refills volume under a set crease | Relaxes muscle and refills the fold together |
| Best for | Dynamic frown, forehead, crow's feet lines | Static folds such as nasolabial lines | Faces showing both dynamic and static wrinkles |
| Pain / comfort | Brief pinches, very tolerable | Numbing used; product contains lidocaine | Managed per area with numbing where needed |
| Downtime | Little to none, occasional tiny bumps | Possible short bruising or swelling | Minimal, depends on filler areas |
| Results timeline | Softening within days, full by 2 weeks | Immediate volume, settles over days | Layered: lines relax, then folds fill |
| Longevity | About 3 to 4 months | Roughly 12 to 24 months by product | Staggered upkeep for each tool |
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